JTT-608

C[C@H]1CC[C@@H](CC1)C(=O)CCC(O)=O

InChIKey=JOWMTYWOBJALGB-KYZUINATSA-N

InChI=1S/C11H18O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h8-9H,2-7H2,1H3,(H,13,14)/t8-,9-

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
insulin secretion 8 Target ID: GO:0030073 Sources: https://www.ncbi.nlm.nih.gov/pubmed/11356916	Activator 1430

PubMed

Title	Date	PubMed
A new hypoglycemic agent, JTT-608, evokes protein kinase A-mediated Ca(2+) signaling in rat islet beta-cells: strict regulation by glucose, link to insulin release, and cooperation with glucagon-like peptide-1(7-36)amide and pituitary adenylate cyclase-activating polypeptide.	2001 Jan	11123358
Daily inhibition of postprandial hyperglycaemia with JTT-608, a novel oral antidiabetic agent, ameliorates pancreatic function in neonatally streptozotocin-treated rats.	2005 Sep	16050944

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:42:56 GMT 2023` Edited by `admin` on `Sat Dec 16 08:42:56 GMT 2023`
Record UNII	U419K07BFP
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

JTT-608

Common Name

English

CYCLOHEXANEBUTANOIC ACID, 4-METHYL-.GAMMA.-OXO-, TRANS-

Systematic Name

English

Code System Code Type Description

FDA UNII

U419K07BFP

Created by admin on Sat Dec 16 08:42:56 GMT 2023 , Edited by admin on Sat Dec 16 08:42:56 GMT 2023

PRIMARY

CAS

195137-72-5

Created by admin on Sat Dec 16 08:42:56 GMT 2023 , Edited by admin on Sat Dec 16 08:42:56 GMT 2023

PRIMARY

PUBCHEM

6919096

Created by admin on Sat Dec 16 08:42:56 GMT 2023 , Edited by admin on Sat Dec 16 08:42:56 GMT 2023

PRIMARY

Related Record Type Details


					U419K07BFP

JTT-608

ACTIVE MOIETY