ENFORTUMAB

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	U1HUE4W970
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ENFORTUMAB

Official Name

English

AGS-22C3

Code

English

ENFORTUMAB [USAN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN NECTIN-4) (HUMAN MONOCLONAL AGS-22C3 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AGS-22C3 LIGHT CHAIN, DIMER

Common Name

English

Code System

Code

Type

Description

NCI_THESAURUS

C169949

PRIMARY

ChEMBL

CHEMBL3301579

PRIMARY

CAS

1448664-46-7

PRIMARY

FDA UNII

U1HUE4W970

PRIMARY

USAN

BC-31

PRIMARY

RXCUI

2268307

PRIMARY

Subunit 0

Subunit 1

Subunit 2

Subunit 3

From	To
1_22	1_96
1_144	1_200
1_261	1_321
1_367	1_425
2_22	2_96
2_144	2_200
2_261	2_321
2_367	2_425
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_220	3_214
2_220	4_214
1_226	2_226
1_229	2_229

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					DLE8519RWM

ENFORTUMAB VEDOTIN

CONJUGATE->CONJUGATE COMPONENT


					2VLM5YIR4K

NECTIN-4

TARGET->LIGAND


					DLE8519RWM

ENFORTUMAB VEDOTIN

PARENT -> DERIVATIVE

Amount:

Related Record Type Details


					U1HUE4W970

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED C6382H9838N1702O2008S46
MOL_WEIGHT(ESTIMATE)	CHEMICAL	144000 Da (average)