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Details

Stereochemistry ACHIRAL
Molecular Formula C18H22ClFN2O3
Molecular Weight 367.833
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLURPIRIDAZ F-18

SMILES

CC(C)(C)N1N=CC(OCC2=CC=C(COCC[18F])C=C2)=C(Cl)C1=O

InChI

InChIKey=RMXZKEPDYBTFOS-LRFGSCOBSA-N
InChI=1S/C18H22ClFN2O3/c1-18(2,3)22-17(23)16(19)15(10-21-22)25-12-14-6-4-13(5-7-14)11-24-9-8-20/h4-7,10H,8-9,11-12H2,1-3H3/i20-1

HIDE SMILES / InChI

Molecular Formula C18H22ClFN2O3
Molecular Weight 367.833
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Flurpiridaz F-18, a fluorine 18-labeled agent was developed by Lantheus Medical Imaging for the diagnosis of coronary artery disease (CAD), the most common form of heart disease, which affects an estimated 15.5 million Americans 20 years of age or older. Flurpiridaz F 18 is an investigational positron emission tomography (PET) myocardial perfusion imaging (MPI) agent. GE Healthcare has launched a second Phase III clinical trial for the use of Flurpiridaz 18F Injection in PET myocardial perfusion imaging (MPI) to detect CAD.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Injection of Flurpiridaz F18 for the purposes of PET myocardial profusion imaging (MPI) analysis
Route of Administration: Intravenous
Substance Class Chemical
Record UNII
TY3V24C029
Record Status Validated (UNII)
Record Version