FOMINOBEN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H24ClN3O3
Molecular Weight	401.887
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(CC(=O)N1CCOCC1)CC2=C(Cl)C=CC=C2NC(=O)C3=CC=CC=C3

InChI

InChIKey=KSNNEUZOAFRTDS-UHFFFAOYSA-N

InChI=1S/C21H24ClN3O3/c1-24(15-20(26)25-10-12-28-13-11-25)14-17-18(22)8-5-9-19(17)23-21(27)16-6-3-2-4-7-16/h2-9H,10-15H2,1H3,(H,23,27)

HIDE SMILES / InChI

Molecular Formula	C21H24ClN3O3
Molecular Weight	401.887
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.medicamentos.com.mx/DocHTM/31249.htm

Fominoben is a medication indicated for the treatment of dry cough. The drug was marketed under the name Noleptan, however, its current status is unknown and supposed to be "discontinued".

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Cough 106 Sources: http://www.medicamentos.com.mx/DocHTM/31249.htm	Primary		Approved 8583	NOLEPTAN Approved Use Indicated for the treatment of irritative dry cough, especially during the night hours; to treat dry cough in smokers or in patients after surgery.

Doses

Dose	Population	Adverse events
160 mg 3 times / day multiple, oral Dose: 160 mg, 3 times / day Route: oral Route: multiple Dose: 160 mg, 3 times / day Sources: https://pubmed.ncbi.nlm.nih.gov/3158563/	unhealthy Health Status: unhealthy Sex: M+F Food Status: UNKNOWN Sources: https://pubmed.ncbi.nlm.nih.gov/3158563/	Sources: https://pubmed.ncbi.nlm.nih.gov/3158563/

PubMed

Title	Date	PubMed
[Evidence-based medicine in urology].	2007-10	18297906

Patents

Sample Use Guides

In Vivo Use Guide

One pill 2-3 times a day.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:35:01 GMT 2025` Edited by `admin` on `Mon Mar 31 18:35:01 GMT 2025`
Record UNII	TJ2KK6NYJS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FOMINOBEN

Official Name

English

PB 89 FREE BASE

Preferred Name

English

3'-CHLORO-.ALPHA.-(METHYL((MORPHOLINOCARBONYL)METHYL)AMINO)-O-BENZOTOLUIDIDE

Common Name

English

PB-89 FREE BASE

Code

English

FOMINOBEN [MI]

Common Name

English

fominoben [INN]

Common Name

English

Fominoben [WHO-DD]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C170002