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Details

Stereochemistry ACHIRAL
Molecular Formula 16C2H5NO2.5I2.4HI
Molecular Weight 2981.7599
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TETRAGLYCINE HYDROPERIODIDE

SMILES

I.I.I.I.II.II.II.II.II.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O

InChI

InChIKey=MHTIPMQDAXVYJV-UHFFFAOYSA-N
InChI=1S/16C2H5NO2.5I2.4HI/c16*3-1-2(4)5;5*1-2;;;;/h16*1,3H2,(H,4,5);;;;;;4*1H

HIDE SMILES / InChI

Molecular Formula I2
Molecular Weight 253.8089
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H5NO2
Molecular Weight 75.0666
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HI
Molecular Weight 127.9124
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Surgicide

Approved Use

Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed
PubMed

PubMed

TitleDatePubMed
[Necrotizing hepatitis with a fatal outcome after carbimazole therapy].
1993 Oct 22
Thyroid adaptation to chronic tetraglycine hydroperiodide water purification tablet use.
1995 Jan
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.
1996 Mar
Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies.
1997 Jul
Adverse reactions to nonionic iodine in contrast-enhanced computed tomography: usefulness of monitoring vital signs.
1998 Jul
Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin.
2001 Feb
Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue.
2003 Jan
Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa.
2004 Feb
Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine.
2005 Nov
Effect of selenium supplementation on activity and mRNA expression of type 1 deiodinase in mice with excessive iodine intake.
2006 Aug
Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation.
2006 Aug 1
Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not hemoglobin in children in Cote d'Ivoire.
2006 Jul
Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway.
2006 Jul 14
The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.
2006 Mar
Antiseptics, iodine, povidone iodine and traumatic wound cleansing.
2006 Nov
Comparative cytotoxicity of high-osmolar and low-osmolar contrast media on HKCs in vitro.
2006 Nov-Dec
The treatment of Graves' disease in children.
2006 Sep
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.
2007 Apr
Goiter and other iodine deficiency disorders: A systematic review of epidemiological studies to deconstruct the complex web.
2007 Jan
[Effects of iodine excess and selenium supplement on the levels of thyroid hormone and its receptor expression in filial cerebrum of mice].
2007 Mar
Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment.
2007 Mar
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
2007 Nov
Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography.
2007 Oct 1
[Suggestions for prevention of adverse reactions after intravasal administration of iodinated contrast media].
2008
[The effects of iodine/selenium on the function of antigen presentation of peritoneal macrophages in rats].
2008 Jul
Gadolinium and kidney disease: are your patients at risk?
2008 Mar-Apr
Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency.
2009 Dec
I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident.
2011 Jul
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.
2012 Aug
Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
2012 Sep 1
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.
2013 Jan
Developmental iodine deficiency delays the maturation of newborn granule neurons associated with downregulation of p35 in postnatal rat hippocampus.
2014 Aug
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 15:51:07 UTC 2023
Edited
by admin
on Fri Dec 15 15:51:07 UTC 2023
Record UNII
T7Y820X70C
Record Status Validated (UNII)
Record Version
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Name Type Language
TETRAGLYCINE HYDROPERIODIDE
MI  
Common Name English
TETRAGLYCINE HYDROPERIODIDE [MI]
Common Name English
GLOBALINE
Common Name English
GLOBALIN
Common Name English
GLYCINE, HYDRIODIDE, COMPD. WITH IODINE (16:4:5)
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 46923
Created by admin on Fri Dec 15 15:51:07 UTC 2023 , Edited by admin on Fri Dec 15 15:51:07 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID0048058
Created by admin on Fri Dec 15 15:51:07 UTC 2023 , Edited by admin on Fri Dec 15 15:51:07 UTC 2023
PRIMARY
CAS
7097-60-1
Created by admin on Fri Dec 15 15:51:07 UTC 2023 , Edited by admin on Fri Dec 15 15:51:07 UTC 2023
PRIMARY
PUBCHEM
76970979
Created by admin on Fri Dec 15 15:51:07 UTC 2023 , Edited by admin on Fri Dec 15 15:51:07 UTC 2023
PRIMARY
FDA UNII
T7Y820X70C
Created by admin on Fri Dec 15 15:51:07 UTC 2023 , Edited by admin on Fri Dec 15 15:51:07 UTC 2023
PRIMARY
MERCK INDEX
m10622
Created by admin on Fri Dec 15 15:51:07 UTC 2023 , Edited by admin on Fri Dec 15 15:51:07 UTC 2023
PRIMARY Merck Index
Related Record Type Details
PARENT -> SALT/SOLVATE