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Details

Stereochemistry ACHIRAL
Molecular Formula 16C2H5NO2.5I2.4HI
Molecular Weight 2981.7599
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TETRAGLYCINE HYDROPERIODIDE

SMILES

I.I.I.I.II.II.II.II.II.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O

InChI

InChIKey=MHTIPMQDAXVYJV-UHFFFAOYSA-N
InChI=1S/16C2H5NO2.5I2.4HI/c16*3-1-2(4)5;5*1-2;;;;/h16*1,3H2,(H,4,5);;;;;;4*1H

HIDE SMILES / InChI

Molecular Formula I2
Molecular Weight 253.8089
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H5NO2
Molecular Weight 75.0666
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HI
Molecular Weight 127.9124
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Surgicide

Approved Use

Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed
PubMed

PubMed

TitleDatePubMed
The susceptibility of the fetus and child to chemical pollutants. Special susceptibility of the host to chemical agents: endocrinologic considerations.
1974 May
[Necrotizing hepatitis with a fatal outcome after carbimazole therapy].
1993 Oct 22
Subfulminant hepatitis requiring liver transplantation after benzarone administration.
1994 Jun
Thyroid adaptation to chronic tetraglycine hydroperiodide water purification tablet use.
1995 Jan
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.
1996 Mar
Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies.
1997 Jul
Adverse reactions to nonionic iodine in contrast-enhanced computed tomography: usefulness of monitoring vital signs.
1998 Jul
Anti-goitrous effect of lecithin-bound iodine in propylthiouracil treated rats.
2000 Jun
Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin.
2001 Feb
Effects of selenium and iodine on the expression of c-fos and c-jun mRNA and their proteins in cultured rat hippocampus neurons.
2002 Jun
Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine.
2003 Apr
Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue.
2003 Jan
Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa.
2004 Feb
Studies on experimental iodine allergy: 3. Low molecular weight elicitogenic antigens of iodine allergy.
2004 May
[Effect of high-iodine intake on MBP mRNA expression in cerebrum of filial mice and selenium intervention].
2005 Jul
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.
2005 Oct
Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation.
2006 Aug 1
The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.
2006 Mar
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.
2007 Apr
[Effects of iodine excess and selenium supplement on the levels of thyroid hormone and its receptor expression in filial cerebrum of mice].
2007 Mar
Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment.
2007 Mar
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
2007 Nov
Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography.
2007 Oct 1
Gadolinium and kidney disease: are your patients at risk?
2008 Mar-Apr
Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency.
2009 Dec
A blinded, randomized, palatability study comparing variations of 2 popular field water disinfection tablets.
2011 Dec
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.
2012 Aug
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.
2013 Jan
Developmental iodine deficiency delays the maturation of newborn granule neurons associated with downregulation of p35 in postnatal rat hippocampus.
2014 Aug
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 15:51:07 GMT 2023
Edited
by admin
on Fri Dec 15 15:51:07 GMT 2023
Record UNII
T7Y820X70C
Record Status Validated (UNII)
Record Version
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Name Type Language
TETRAGLYCINE HYDROPERIODIDE
MI  
Common Name English
TETRAGLYCINE HYDROPERIODIDE [MI]
Common Name English
GLOBALINE
Common Name English
GLOBALIN
Common Name English
GLYCINE, HYDRIODIDE, COMPD. WITH IODINE (16:4:5)
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 46923
Created by admin on Fri Dec 15 15:51:07 GMT 2023 , Edited by admin on Fri Dec 15 15:51:07 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID0048058
Created by admin on Fri Dec 15 15:51:07 GMT 2023 , Edited by admin on Fri Dec 15 15:51:07 GMT 2023
PRIMARY
CAS
7097-60-1
Created by admin on Fri Dec 15 15:51:07 GMT 2023 , Edited by admin on Fri Dec 15 15:51:07 GMT 2023
PRIMARY
PUBCHEM
76970979
Created by admin on Fri Dec 15 15:51:07 GMT 2023 , Edited by admin on Fri Dec 15 15:51:07 GMT 2023
PRIMARY
FDA UNII
T7Y820X70C
Created by admin on Fri Dec 15 15:51:07 GMT 2023 , Edited by admin on Fri Dec 15 15:51:07 GMT 2023
PRIMARY
MERCK INDEX
m10622
Created by admin on Fri Dec 15 15:51:07 GMT 2023 , Edited by admin on Fri Dec 15 15:51:07 GMT 2023
PRIMARY Merck Index
Related Record Type Details
PARENT -> SALT/SOLVATE