Suvemcitug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:35:33 UTC 2023` Edited by `admin` on `Sat Dec 16 19:35:33 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	T7Y5VC4ERJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Suvemcitug

Official Name

English

APX-003

Code

English

APX 003

Code

English

immunoglobulin G1-kappa, anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF)], humanized monoclonal antibody (gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV3-21*01 (74.7%) -(IGHD) -IGHJ2*01 (92.9%), CDR-IMGT [9.8.14

Common Name

English

suvemcitug [INN]

Common Name

English

BD-0801

Code

English

Sevacizumab

Common Name

English

Immunoglobulin G1, anti-(human vascular endothelial growth factor) (human-Oryctolagus cuniculus monoclonal APX 003 γ1-chain), disulfide with human-Oryctolagus cuniculus monoclonal APX 003 κ-chain, dimer

Common Name

English

Code System Code Type Description

FDA UNII

T7Y5VC4ERJ

Created by admin on Sat Dec 16 19:35:33 UTC 2023 , Edited by admin on Sat Dec 16 19:35:33 UTC 2023

PRIMARY

NCI_THESAURUS

C122403

Created by admin on Sat Dec 16 19:35:33 UTC 2023 , Edited by admin on Sat Dec 16 19:35:33 UTC 2023

PRIMARY

INN

12428

Created by admin on Sat Dec 16 19:35:33 UTC 2023 , Edited by admin on Sat Dec 16 19:35:33 UTC 2023

PRIMARY

CAS

1610010-57-5

Created by admin on Sat Dec 16 19:35:33 UTC 2023 , Edited by admin on Sat Dec 16 19:35:33 UTC 2023

PRIMARY

From	To
4_139	4_199
4_90	4_139
3_199	4_23
3_90	3_139
2_430	3_23
2_326	2_372
2_266	4_219
2_205	2_225
2_97	2_149
1_430	2_22
1_326	1_372
1_266	2_234
1_234	2_231
1_231	3_219
1_205	1_225
1_149	1_205
1_22	1_97

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
N	2_302

Related Record Type Details


					NZN256ZSV8

HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A

TARGET->LIGAND

Amount:

Related Record Type Details


					T7Y5VC4ERJ

Suvemcitug

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL