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Details

Stereochemistry RACEMIC
Molecular Formula C18H21NO2
Molecular Weight 283.3648
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYLNAPHTHIDATE

SMILES

[H][C@@]1(CCCCN1)[C@H](C(=O)OC)C2=CC3=CC=CC=C3C=C2

InChI

InChIKey=DNRNSIJBSCBESJ-IAGOWNOFSA-N
InChI=1S/C18H21NO2/c1-21-18(20)17(16-8-4-5-11-19-16)15-10-9-13-6-2-3-7-14(13)12-15/h2-3,6-7,9-10,12,16-17,19H,4-5,8,11H2,1H3/t16-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula C18H21NO2
Molecular Weight 283.3648
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 11:23:37 UTC 2023
Edited
by admin
on Sat Dec 16 11:23:37 UTC 2023
Record UNII
T52Y9T2U0W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METHYLNAPHTHIDATE
Common Name English
METHYL 2-(NAPHTHALEN-2-YL)-2-(PIPERIDIN-2-YL)ACETATE
Systematic Name English
2-PIPERIDINEACETIC ACID, .ALPHA.-2-NAPHTHALENYL-, METHYL ESTER, (.ALPHA.R,2R)-REL-
Systematic Name English
2-PIPERIDINEACETIC ACID, .ALPHA.-2-NAPHTHALENYL-, METHYL ESTER
Systematic Name English
DL-THREO-METHYLNAPHTHIDATE
Common Name English
HDMP-28
Common Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-HDMP-28
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
Code System Code Type Description
FDA UNII
T52Y9T2U0W
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
PRIMARY
WEB RESOURCE
HDMP-28
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
PRIMARY
WIKIPEDIA
HDMP-28
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
PRIMARY HDMP-28 or methylnaphthidate is a piperidine based stimulant drug, closely related to methylphenidate, but with the benzene ring replaced by naphthalene. It is a potent dopamine reuptake inhibitor, with several times the potency of methylphenidate and a short duration of action, and is a structural isomer of another potent dopamine reuptake inhibitor, N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate.
MANUFACTURER PRODUCT INFORMATION
METHYLNAPHTHIDATE
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
PRIMARY HDMP-28 is a methylphenidate (ritalin, concerta) analogue which replaces the phenyl moiety with a naphthyl moiety. The modification confers a theoretical increase in SERT affinity, making effects closer to cocaine, and also theoretically gives increased potency over methylphenidate. Despite being known about in scientific literature for many years, HDMP-28 is unusual in that it did not come to market until 2014. This is in stark contrast to many other known recreational drug analogues which were primarily surrected from the literature between 2010-2013.
CAS
1607459-83-5
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
NON-SPECIFIC STEREOCHEMISTRY
CAS
231299-82-4
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
PRIMARY
PUBCHEM
9817261
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
PRIMARY
EPA CompTox
DTXSID201027520
Created by admin on Sat Dec 16 11:23:37 UTC 2023 , Edited by admin on Sat Dec 16 11:23:37 UTC 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY