SILTUXIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 20:38:12 GMT 2025` Edited by `admin` on `Mon Mar 31 20:38:12 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	T4H8FMA7IM
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SILTUXIMAB

Official Name

English

SYLVANT

Preferred Name

English

SILTUXIMAB [VANDF]

Common Name

English

SILTUXIMAB [USAN]

Common Name

English

siltuximab [INN]

Common Name

English

CNTO-328

Code

English

SILTUXIMAB [MI]

Common Name

English

SILTUXIMAB [PURPLE BOOK CDER]

Common Name

English

CNTO328

Code

English

CLLB8

Code

English

Siltuximab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 6) (HUMAN-MOUSE MONOCLONAL CNTO 328 HEAVY CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CNTO 328 K-CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129822

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

EU-Orphan Drug

EU/3/07/508

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

FDA ORPHAN DRUG

200505

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

FDA ORPHAN DRUG

200605

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

EMA ASSESSMENT REPORTS

SYLVANT (AUTHORIZED: GIANT LYMPH NODE HYPERPLASIA)

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

WHO-ATC

L04AC11

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

NDF-RT

N0000191006

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

Code System Code Type Description

FDA UNII

T4H8FMA7IM

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

MERCK INDEX

m11726

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

NCI_THESAURUS

C61084

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

LACTMED

Siltuximab

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

CAS

541502-14-1

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

IUPHAR

7396

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

USAN

WW-87

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

DRUG BANK

DB09036

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

WIKIPEDIA

SILTUXIMAB

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

ChEMBL

CHEMBL1743070

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

EVMPD

SUB32552

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

DAILYMED

T4H8FMA7IM

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

SMS_ID

100000124530

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

RXCUI

1535218

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

RxNorm

NDF-RT

N0000191004

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

Interleukin-6 Antagonists [MoA]

DRUG CENTRAL

4977

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

INN

9051

Created by admin on Mon Mar 31 20:38:12 GMT 2025 , Edited by admin on Mon Mar 31 20:38:12 GMT 2025

PRIMARY

From	To
1_22	1_96
1_146	1_202
1_263	1_323
1_369	1_427
2_22	2_96
2_146	2_202
2_263	2_323
2_369	2_427
3_23	3_87
3_133	3_193
4_23	4_87
4_133	4_193
1_222	3_213
2_222	4_213
1_228	2_228
1_231	2_231

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					T4H8FMA7IM

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL