E-3040

CNC1=NC2=C(S1)C(C)=C(O)C(C)=C2CC3=CN=CC=C3

InChIKey=IONAQTGMWFXHIX-UHFFFAOYSA-N

InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)13-15(10(2)14(9)20)21-16(17-3)19-13/h4-6,8,20H,7H2,1-3H3,(H,17,19)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs.	2011-02	21272127
Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4.	2009-10	19628752
Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen.	2005-03	15598971
Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice.	2004-09	15319327

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:42:14 GMT 2025` Edited by `admin` on `Mon Mar 31 23:42:14 GMT 2025`
Record UNII	T4AB9WQ98U
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

E-3040

Code

English

E 3040

Preferred Name

English

6-HYDROXY-5,7-DIMETHYL-2-METHYLAMINO-4-(3-PYRIDYLMETHYL)BENZOTHIAZOLE

Common Name

English

5,7-DIMETHYL-2-(METHYLAMINO)-4-(3-PYRIDINYLMETHYL)-6-BENZOTHIAZOLOL

Systematic Name

English

6-BENZOTHIAZOLOL, 5,7-DIMETHYL-2-(METHYLAMINO)-4-(3-PYRIDINYLMETHYL)-

Systematic Name

English

E3040

Code

English

Code System Code Type Description

CHEBI

4732