Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H17Br2NO2.ClH.H2O |
| Molecular Weight | 433.564 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.Cl.O[C@H]1CC[C@@H](CC1)NCC2=C(O)C(Br)=CC(Br)=C2
InChI
InChIKey=GZLZRWMDTSWUDJ-SOBFFWEGSA-N
InChI=1S/C13H17Br2NO2.ClH.H2O/c14-9-5-8(13(18)12(15)6-9)7-16-10-1-3-11(17)4-2-10;;/h5-6,10-11,16-18H,1-4,7H2;1H;1H2/t10-,11-;;
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C13H17Br2NO2 |
| Molecular Weight | 379.088 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/3363832 | http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500013623.pdf
Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/3363832 | http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500013623.pdf
Dembrexine is a mucolytic agent which reduces the viscosity of respiratory mucus. It improves movement of mucus in small airways. Dembrexine increases secretion of the serous cells in the glands of the nasal, tracheal and bronchial cells and in type II alveolar cells. It also possesses an anti-tussive effect. Dembrexine is used in the treatment of respiratory disease in horses. All respiratory infections with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection of the upper airways.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: GO:0043129 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Palliative | Sputolosin Approved UseThe drug is indicated for the treatment of respiratory disease in horses. All respiratory infections
with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection
of the upper airways. |
|||
| Palliative | Sputolosin Approved UseThe drug is indicated for the treatment of respiratory disease in horses. All respiratory infections
with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection
of the upper airways. |
|||
| Palliative | Sputolosin Approved UseThe drug is indicated for the treatment of respiratory disease in horses. All respiratory infections
with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection
of the upper airways. |
|||
| Palliative | Sputolosin Approved UseThe agent is indicated for the treatment of foal pneumonia. |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:10:19 GMT 2023
by
admin
on
Fri Dec 15 19:10:19 GMT 2023
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| Record UNII |
SZ936TIM8E
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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300000029157
Created by
admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
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SZ936TIM8E
Created by
admin on Fri Dec 15 19:10:19 GMT 2023 , Edited by admin on Fri Dec 15 19:10:19 GMT 2023
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PARENT -> SALT/SOLVATE | |||
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ANHYDROUS->SOLVATE |
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ACTIVE MOIETY |