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Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 02:31:21 UTC 2023
Edited
by admin
on Sat Dec 16 02:31:21 UTC 2023
Protein Type HORMONE
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
SQ6SA9L9XQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLUCAGON-LIKE PEPTIDE 1
Common Name English
GLUCAGON-LIKE PEPTIDE 1, HUMAN
Common Name English
GLP-1
Common Name English
HUMAN GLUCAGON-LIKE PEPTIDE 1
Common Name English
GLP-1 [MI]
Common Name English
Code System Code Type Description
PUBCHEM
16131070
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
PRIMARY
CAS
89750-14-1
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
ALTERNATIVE
WIKIPEDIA
GLUCAGON-LIKE PEPTIDE-1
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
PRIMARY
EPA CompTox
DTXSID10236651
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
PRIMARY
MESH
D052216
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
PRIMARY
EVMPD
SUB179551
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
PRIMARY
CAS
87805-34-3
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
PRIMARY
FDA UNII
SQ6SA9L9XQ
Created by admin on Sat Dec 16 02:31:21 UTC 2023 , Edited by admin on Sat Dec 16 02:31:21 UTC 2023
PRIMARY
Related Record Type Details
ACTIVATOR OF EXPRESSION->TARGET
Acarbose treatment stimulates postprandial GLP-1 secretion in patients with type 2 diabetes. Dependent on dose and saccharide or polysaccharide present. A single dose of 100 mg acarbose during an oral sucrose (disaccharide) load resulted in elevated GLP-1 levels compared to placebo (8, 10, 28, 29) whereas no effect was seen during oral glucose tolerance test (24), emphasizing that acarbose needs relevant carbohydrates to ‘act on’ in order to increase GLP-1 secretion. A single dose of 100 mg acarbose during an oral sucrose (disaccharide) load resulted in elevated GLP-1 levels compared to placebo (8, 10, 28, 29) whereas no effect was seen during oral glucose tolerance test (24), emphasizing that acarbose needs relevant carbohydrates to ‘act on’ in order to increase GLP-1 secretion.
AGONIST -> TARGET
AGONIST -> TARGET
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL