Mevonlerbart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:46:26 GMT 2023` Edited by `admin` on `Sat Dec 16 14:46:26 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	SN982PAN4O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Mevonlerbart

Official Name

English

mevonlerbart [INN]

Common Name

English

immunoglobulin G4-kappa, anti-[Fel d 1 (Felis silvestris catus (domestic cat) allergen 1)], Homo sapiens monoclonal antibody

Common Name

English

gamma4 heavy chain Homo sapiens (1-442) [VH (Homo sapiens IGHV3-23*04 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92 (CH1(116-213), hinge 1-12 S10>P (223) (214-225), CH2

Common Name

English

Immunoglobulin G4 [223-proline], anti-(Felis catus allergen Fel d1) (human monoclonal REGN1909 γ4-chain), disulfide with human monoclonal REGN1909 κ-chain, dimer

Common Name

English

REGN1909

Code

English

REGN-1909

Code

English

ANTI-CAT ALLERGEN FEL D 1 MONOCLONAL ANITBODY REGN-1909

Common Name

English

Code System Code Type Description

INN

12256

Created by admin on Sat Dec 16 14:46:26 GMT 2023 , Edited by admin on Sat Dec 16 14:46:26 GMT 2023

PRIMARY

FDA UNII

SN982PAN4O

Created by admin on Sat Dec 16 14:46:26 GMT 2023 , Edited by admin on Sat Dec 16 14:46:26 GMT 2023

PRIMARY

CAS

2453195-99-6

Created by admin on Sat Dec 16 14:46:26 GMT 2023 , Edited by admin on Sat Dec 16 14:46:26 GMT 2023

PRIMARY

NCI_THESAURUS

C190485

Created by admin on Sat Dec 16 14:46:26 GMT 2023 , Edited by admin on Sat Dec 16 14:46:26 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_129	4_214
2_142	2_198
2_256	2_316
1_129	3_214
2_362	2_420
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_142	1_198
1_221	2_221
1_224	2_224
1_256	1_316
1_362	1_420

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_292
N	2_292

Related Record Type Details


					G408EE88II

ALLERGEN FEL D 1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					SN982PAN4O

Mevonlerbart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL