NBI-35965 FREE BASE

CC[C@H]1CN2N=C(C3=NC(C)=CC(N1CC4CC4)=C23)C5=CC=C(Cl)C=C5Cl

InChIKey=SUCZRVASFXLXDM-HNNXBMFYSA-N

InChI=1S/C21H22Cl2N4/c1-3-15-11-27-21-18(26(15)10-13-4-5-13)8-12(2)24-20(21)19(25-27)16-7-6-14(22)9-17(16)23/h6-9,13,15H,3-5,10-11H2,1-2H3/t15-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
Corticotropin releasing factor receptor 1 8 Target ID: CHEMBL1800 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12957366	Antagonist 2778		4.0 nM [Ki]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:41:05 GMT 2023` Edited by `admin` on `Sat Dec 16 08:41:05 GMT 2023`
Record UNII	SFQ6J6N9F3
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

NBI-35965 FREE BASE

Common Name

English

6H-1,3,6,8A-TETRAAZAACENAPHTHYLENE, 6-(CYCLOPROPYLMETHYL)-2-(2,4-DICHLOROPHENYL)-7-ETHYL-7,8-DIHYDRO-4-METHYL-, (7S)-

Systematic Name

English

(10S)-9-(CYCLOPROPYLMETHYL)-3-(2,4-DICHLOROPHENYL)-10-ETHYL-6-METHYL-1,2,5,9-TETRAAZATRICYCLO(6.3.1.0(4,12))DODECA-2,4,6,8(12)-TETRAENE

Systematic Name

English

Code System Code Type Description

CAS

268546-19-6

Created by admin on Sat Dec 16 08:41:05 GMT 2023 , Edited by admin on Sat Dec 16 08:41:05 GMT 2023

PRIMARY

PUBCHEM

11713007

Created by admin on Sat Dec 16 08:41:05 GMT 2023 , Edited by admin on Sat Dec 16 08:41:05 GMT 2023

PRIMARY

FDA UNII

SFQ6J6N9F3

Created by admin on Sat Dec 16 08:41:05 GMT 2023 , Edited by admin on Sat Dec 16 08:41:05 GMT 2023

PRIMARY

Related Record Type Details


					SFQ6J6N9F3

ACTIVE MOIETY