U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula CS2
Molecular Weight 76.141
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CARBON DISULFIDE

SMILES

S=C=S

InChI

InChIKey=QGJOPFRUJISHPQ-UHFFFAOYSA-N
InChI=1S/CS2/c2-1-3

HIDE SMILES / InChI

Molecular Formula CS2
Molecular Weight 76.141
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Carbon disulfide (CS2) in its pure form is a colourless, volatile and in-flammable liquid with a sweet aromatic odour. The technical product is a yellowish liquid with a disagreeable odour. It has been an important industrial chemical since the 1800s because of its many useful properties, including its ability to solubilise fats, rubbers, phosphorus, sulfur, and other elements. Its fat-solvent properties also make it indispensable in preparing fats, lacquers, and camphor; in refining petroleum jelly and paraffin; and in extracting oil from bones, palmstones, olives, and rags. It was also used in processing India rubber sap from tropical trees. In all these extraction processes, it has now been replaced by other solvents. Carbon disulfide's most important industrial use has been in the manufacture of regenerated cellulose rayon (by the viscose process) and cellophane. Another principal industrial use for carbon disulfide has been as a feedstock for carbon tetrachloride production. It has also been used to protect fresh fruit from insects and fungus during shipping, in adhesives for food packaging, and in the solvent extraction of growth inhibitors. Carbon disulfide has been highly suitable for other industrial applications including the vulcanisation and manufacture of rubber and rubber accessories; the production of resins, xanthates, thiocyanates, plywood adhesives, and flotation agents; solvent and spinning-solution applications, primarily in the manufacture of rayon and polymerisation inhibition of vinyl chloride; conversion and processing of hydrocarbons; petroleum-well cleaning; brightening of precious metals in electroplating; rust removal from metals; and removal and recovery of metals and other elements from waste water and other media. In agriculture, carbon disulfide has been widely used as a fumigant to control insects in stored grain, and to remove botfly larva infestations from the stomachs of horses and ectoparasites from swine. Use of carbon disulfide as a grain fumigant in the USA was voluntarily cancelled after 1985. The primary source of carbon disulfide in the environment is emission from viscose plants, around which environmental pollution is especially great. Carbon disulfide is irritating to the eyes, mucous membranes, and skin. Acute neurological effects may result from all routes of exposure and may include headache, confusion, psychosis, and coma. Acute exposure to extremely high levels of carbon disulfide may result in death. The neurotoxic effects caused by carbon disulfide may be due, in part, to its metabolic conversion to dithiocarbamates. Individuals especially susceptible to the toxic effects of carbon disulfide include those with existing disorders of the nervous system, respiratory system, cardiovascular system, or eyes.

Approval Year

PubMed

PubMed

TitleDatePubMed
Disassociation of carbon disulfide-induced depression of flash-evoked potential peak N166 amplitude and norepinephrine levels.
2003-06
Inhalation toxicity of propineb. Part II: Results of mechanistic studies in rats.
2003-04-25
Synthesis of some new pyrimidine and fused pyrimidine derivatives (Part I).
2003-04-23
[Reference values of solvents and metabolites in biological samples].
2003-04-17
Novel double insertion of carbon disulfide into two Ru-H bonds of [(dppm)(2)Ru(H)(2)] (dppm = Ph(2)PCH(2)PPh(2)): synthesis and crystal structure of a methanedithiolate complex.
2003-02-10
A new reactivity pattern of low-valent transition-metal hydroxo complexes: straightforward synthesis of hydrosulfido complexes via reaction with carbon disulfide.
2003-02-07
Cardiovascular function of workers exposed to carbon disulphide.
2003-02
Pressure broadening study of carbon disulfide for atmospheric detection.
2003-02
Synthesis of anellated carbasugars from (--)-quinic acid.
2003-01-31
Determination of carbon disulfide at the workplace by sampling on charcoal tubes--problems and solutions.
2003-01-18
Cerebellar atrophy as a delayed manifestation of chronic carbon disulfide poisoning.
2003-01
Elevated triglyceride and decreased high density lipoprotein level in carbon disulfide workers in Taiwan.
2003-01
Color vision and occupational chemical exposures: I. An overview of tests and effects.
2002-12
New 2H-tetrahydro-1, 3, 5-thiadiazine-2-thiones incorporating glycine and glycinamide as potential antifungal agents.
2002-11
Long-term neuropsychological effects and MRI findings in patients with CS2 poisoning.
2002-11
Cardiovascular effects of carbon disulfide: meta-analysis of cohort studies.
2002-10
Death by paint thinner.
2002-10
Assessment of the correlation between exposure to benzene and urinary excretion of t, t-muconic acid in workers from a petrochemical plant.
2002-10
Brain MRI findings of carbon disulfide poisoning.
2002-09-25
Alcohol and urinary 2-thiothiazolidine-4-carboxylic acid.
2002-08-05
Bioassay of three sulphur containing compounds as rat attractant admixed in cereal-based bait against Rattus rattus Linn.
2002-08
Trace determination of volatile sulfur compounds by solid-phase microextraction and GC-MS.
2002-08
A laboratory technique for investigation of diffusion and transformation of volatile organic compounds in low permeability media.
2002-08
Critical review of the epidemiological literature on the potential cardiovascular effects of occupational carbon disulfide exposure.
2002-08
Quantification of volatile sulfur compounds in complex gaseous matrices by solid-phase microextraction.
2002-07-19
Volatile sulfur compounds in irradiated precooked turkey breast analyzed with pulsed flame photometric detection.
2002-07-17
Convenient syntheses of symmetrical and unsymmetrical glycosyl carbodiimides and N,N-bis(glycosyl)cyanamides.
2002-07-16
Breath biomarkers for detection of human liver diseases: preliminary study.
2002-07-10
Cross-sectional study of the ophthalmological effects of carbon disulfide in Chinese viscose workers.
2002-07
Effects of the dithiocarbamate fungicide propineb in primary neuronal cell cultures and skeletal muscle cells of the rat.
2002-07
Separation and determination of emetine dithiocarbamate metal complexes by capillary electrophoresis with chemiluminescence detection of the tris(2,2'-bipyridine)-ruthenium(II) complex.
2002-06-07
Off-resonant fifth-order response function for two-dimensional Raman spectroscopy of liquids CS2 and H2O.
2002-05-20
Clinical course in patients with chronic carbon disulfide polyneuropathy.
2002-05
Vanadium nitride functionalization and denitrogenation by carbon disulfide and dioxide.
2002-04-21
Increased oxidative stress in subjects exposed to carbon disulfide (CS2)--an occupational coronary risk factor.
2002-04
Quantum calculation of highly excited vibrational energy levels of CS2(X) on a new empirical potential energy surface and semiclassical analysis of 1:2 Fermi resonance.
2002-03-01
Gas-phase analysis of trimethylamine, propionic and butyric acids, and sulfur compounds using solid-phase microextraction.
2002-03-01
[The conversion from CS2 to COS by spark discharge].
2002-03
Effectiveness of selected chemicals for controlling emission of malodorous sulfur gases in sewage sludge.
2002-03
Thioalkalivibrio thiocyanoxidans sp. nov. and Thioalkalivibrio paradoxus sp. nov., novel alkaliphilic, obligately autotrophic, sulfur-oxidizing bacteria capable of growth on thiocyanate, from soda lakes.
2002-03
Viscosity dependence of optical limiting in carbon black suspensions.
2002-02-20
Biological monitoring of carbon disulphide: kinetics of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA) in exposed workers.
2002-02
Theoretical study on the mechanism of the gas-phase reaction of diborane(3) anion with carbon disulfide.
2002-02
[Improvement of the determination method of benzene, toluene, ethylbenzene and xylene(BTEX) in water using activated carbon fiber solid-phase microextraction/gas chromatography-mass spectrometry(GC-MS)].
2002-01
Characterization of wastewater and solids odors using solid phase microextraction at a large wastewater treatment plant.
2002
Effects of occupational exposure to a mixture of solvents on the inner ear: a field study.
2002
Carbon disulfide cytotoxicity on cultured cardiac myocytes of rats.
2002
Adjusted active carbon fibers for solid phase microextraction.
2002
[Study on FM100-HUE color vision in male workers exposed to lower concentration of carbon disulfide].
2001-05
Product distribution during transformation of multiple contaminants by a high-rate, tetrachlorethene-dechlorinating enrichment culture.
2001
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:16:03 GMT 2025
Edited
by admin
on Mon Mar 31 18:16:03 GMT 2025
Record UNII
S54S8B99E8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CARBON DISULFIDE
HSDB   ISO   MART.   MI  
Systematic Name English
CARBONEUM SULPHURATUM
HPUS  
Preferred Name English
CARBON DISULFIDE [MI]
Common Name English
Carbon disulfide [WHO-DD]
Common Name English
CARBON DISULFIDE [MART.]
Common Name English
CARBONEUM SULPHURATUM [HPUS]
Common Name English
CARBON DISULFIDE [HSDB]
Common Name English
CARBON BISULFIDE
Common Name English
CARBON DISULFIDE [ISO]
Common Name English
CARBON DISULFIDE [GREEN BOOK]
Common Name English
CARBON BISULPHIDE
Common Name English
CARBON DISULPHIDE
Systematic Name English
NCI-C04591
Common Name English
Classification Tree Code System Code
CFR 21 CFR 520.1802B
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
CFR 21 CFR 520.1802A
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
NCI_THESAURUS C718
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
CFR 21 CFR 520.1802
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
CFR 21 CFR 520.1802C
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
Code System Code Type Description
PUBCHEM
6348
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
HSDB
51
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
MERCK INDEX
m3081
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY Merck Index
ECHA (EC/EINECS)
200-843-6
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
FDA UNII
S54S8B99E8
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
MESH
D002246
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
SMS_ID
300000053190
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
EPA CompTox
DTXSID6023947
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
CAS
75-15-0
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
NCI_THESAURUS
C29813
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
CHEBI
23012
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
WIKIPEDIA
CARBON DISULFIDE
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
DAILYMED
S54S8B99E8
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
ALANWOOD
carbon disulfide
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY
RXCUI
1311478
Created by admin on Mon Mar 31 18:16:03 GMT 2025 , Edited by admin on Mon Mar 31 18:16:03 GMT 2025
PRIMARY RxNorm
Related Record Type Details
ACTIVE MOIETY