U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H6ClNO3S
Molecular Weight 159.592
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-Chlorotaurine

SMILES

OS(=O)(=O)CCNCl

InChI

InChIKey=NMMHHSLZJLPMEG-UHFFFAOYSA-N
InChI=1S/C2H6ClNO3S/c3-4-1-2-8(5,6)7/h4H,1-2H2,(H,5,6,7)

HIDE SMILES / InChI

Molecular Formula C2H6ClNO3S
Molecular Weight 159.592
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Mon Mar 31 19:09:27 GMT 2025
Edited
by admin
on Mon Mar 31 19:09:27 GMT 2025
Record UNII
S3ZHQ09WZ5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ACU-NCT-001
Preferred Name English
N-Chlorotaurine
Systematic Name English
NCT
Code English
TAURINE CHLORAMINE
Systematic Name English
ETHANESULFONIC ACID, 2-(CHLOROAMINO)-
Systematic Name English
ATV-02
Code English
2-(CHLOROAMINO)ETHANESULFONIC ACID
Systematic Name English
Code System Code Type Description
MESH
C043410
Created by admin on Mon Mar 31 19:09:27 GMT 2025 , Edited by admin on Mon Mar 31 19:09:27 GMT 2025
PRIMARY
PUBCHEM
108018
Created by admin on Mon Mar 31 19:09:27 GMT 2025 , Edited by admin on Mon Mar 31 19:09:27 GMT 2025
PRIMARY
FDA UNII
S3ZHQ09WZ5
Created by admin on Mon Mar 31 19:09:27 GMT 2025 , Edited by admin on Mon Mar 31 19:09:27 GMT 2025
PRIMARY
CAS
51036-13-6
Created by admin on Mon Mar 31 19:09:27 GMT 2025 , Edited by admin on Mon Mar 31 19:09:27 GMT 2025
PRIMARY
DRUG BANK
DB06633
Created by admin on Mon Mar 31 19:09:27 GMT 2025 , Edited by admin on Mon Mar 31 19:09:27 GMT 2025
PRIMARY
EPA CompTox
DTXSID80199047
Created by admin on Mon Mar 31 19:09:27 GMT 2025 , Edited by admin on Mon Mar 31 19:09:27 GMT 2025
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY
Being a mild oxidant, NCT proved to be very well tolerated by human tissue in Phase I and II clinical studies. A 1% aqueous solution can be applied to the eye, skin ulcerations, outer ear canal, nasal and paranasal sinuses, oral cavity and urinary bladder, and can probably be used for inhalation. Therapeutic efficacy in Phase II studies has been shown in external otitis, purulently coated crural ulcerations and keratoconjunctivitis, so far. Based upon all presently available data, NCT seems to be an antiseptic with a very good relation between tolerability and activity.