VAMICAMIDE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H23N3O
Molecular Weight	297.3947
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](C[C@@](C(N)=O)(C1=CC=CC=C1)C2=NC=CC=C2)N(C)C

InChI

InChIKey=BWNLUIXQIHPUGO-RDTXWAMCSA-N

InChI=1S/C18H23N3O/c1-14(21(2)3)13-18(17(19)22,15-9-5-4-6-10-15)16-11-7-8-12-20-16/h4-12,14H,13H2,1-3H3,(H2,19,22)/t14-,18-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C18H23N3O
Molecular Weight	297.3947
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8595084 | https://www.ncbi.nlm.nih.gov/pubmed/8176715 | https://www.thepharmaletter.com/article/vamicamide-pulled

Vamicamide [FK 176, Urocut®] is an antagonist of muscarinic receptors, developed by Japanese company Fujisawa for the treatment of urinary incontinence. Fujisawa has withdrawn its application to market vamicamide because confirmatory studies conducted with the drug since the application have failed to show any superiority for vamicamide over an active control medication.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:57:33 GMT 2023` Edited by `admin` on `Fri Dec 15 15:57:33 GMT 2023`
Record UNII	RU10K34QRU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VAMICAMIDE

Official Name

English

vamicamide [INN]

Common Name

English

(±)-(R*)-.ALPHA.-((R*)-2-(DIMETHYLAMINO)PROPYL)-.ALPHA.-PHENYL-2-PYRIDINEACETAMIDE

Systematic Name

English

VAMICAMIDE [MI]

Common Name

English

VAMICAMIDE [JAN]

Common Name

English

2-PYRIDINEACETAMIDE, .ALPHA.-((2R)-2-(DIMETHYLAMINO)PROPYL)-.ALPHA.-PHENYL-, (.ALPHA.R)-REL-

Common Name

English

FK-176

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29704