Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Wed Apr 02 19:13:50 GMT 2025
by
admin
on
Wed Apr 02 19:13:50 GMT 2025
|
| Source Materials Class | ORGANISM |
| Source Materials Type | AUTOLOGOUS HUMAN |
| Source Materials State | LIVE GENETICALLY MODIFIED |
| Source Materials Parent | |
| Part | BLOOD |
| Fraction Material Type | CELL |
| Fraction Name | CD4+/CD8+ T cells |
| Record UNII |
RSC598M6W5
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
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Preferred Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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RSC598M6W5
Created by
admin on Wed Apr 02 19:13:50 GMT 2025 , Edited by admin on Wed Apr 02 19:13:50 GMT 2025
|
PRIMARY | |||
|
13540
Created by
admin on Wed Apr 02 19:13:50 GMT 2025 , Edited by admin on Wed Apr 02 19:13:50 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET->CYTOTOXIC T-CELL |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
|
Agent Modifications
| Modification Process | Modification Role | Modification Type | Amount | Fragment Name | Fragment ID |
|---|---|---|---|---|---|
| RETROVIRAL TRANSFECTION | TRANSFECTION | GENE MODIFICATION |
|
UNSPECIFIED SUBSTANCE | 3c2e4589 |
| EXPANSION | BIOLOGICAL |
|
|||
| CULTURE | ACTIVATOR | BIOLOGICAL |
|
T CELL TRANSACT, HUMAN | YG578HEY4V |
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| VECTOR EXPRESSED PROTEIN | Olmocabtagene autoleucel expressed chimeric antigen receptor targeting CLDN6 | Q8X69M34BE | ||||
| INSERTED GENE EXPRESSION VECTOR | Olmocabtagene autoleucel transgene insert encoding a chimeric antigen receptor targeting claudin 6 | P4558453G3 |