TAK-778

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H28NO7PS
Molecular Weight	505.52
Optical Activity	( - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOP(=O)(CC1=CC=C(NC(=O)[C@H]2CC3=CC4=C(OCO4)C=C3C(=O)[C@H](C)S2)C=C1)OCC

InChI

InChIKey=WXACSCNLLDFZHE-OYHNWAKOSA-N

InChI=1S/C24H28NO7PS/c1-4-31-33(28,32-5-2)13-16-6-8-18(9-7-16)25-24(27)22-11-17-10-20-21(30-14-29-20)12-19(17)23(26)15(3)34-22/h6-10,12,15,22H,4-5,11,13-14H2,1-3H3,(H,25,27)/t15-,22+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H28NO7PS
Molecular Weight	505.52
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Sustained-release microcapsules of a bone formation stimulant, TAK-778, for local injection into a fracture site.	2001 Dec	11745771

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:38:00 GMT 2023` Edited by `admin` on `Sat Dec 16 11:38:00 GMT 2023`
Record UNII	RJF24P5QDS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TAK-778

Code

English

PHOSPHONIC ACID, ((4-(((5,6,8,9-TETRAHYDRO-8-METHYL-9-OXOTHIEPINO(4,5-F)-1,3-BENZODIOXOL-6-YL)CARBONYL)AMINO)PHENYL)METHYL)-, DIETHYL ESTER, (6R-TRANS)-

Systematic Name

English

TAK-778-SR

Code

English

PHOSPHONIC ACID, ((4-((((6R,8S)-5,6,8,9-TETRAHYDRO-8-METHYL-9-OXOTHIEPINO(4,5-F)-1,3-BENZODIOXOL-6-YL)CARBONYL)AMINO)PHENYL)METHYL)-, DIETHYL ESTER

Common Name

English

TAK778

Code

English

DIETHYL 4-((6R,8S)-8-METHYL-9-OXO-5,6,8,9-TETRAHYDROTHIEPINO(4',5':4,5)BENZO(1,2-D)(1,3)DIOXOLE-6-CARBOXAMIDO)BENZYLPHOSPHONATE

Systematic Name

English

Code System Code Type Description

CAS

180185-61-9

Created by admin on Sat Dec 16 11:38:00 GMT 2023 , Edited by admin on Sat Dec 16 11:38:00 GMT 2023

PRIMARY

PUBCHEM

9806177

Created by admin on Sat Dec 16 11:38:00 GMT 2023 , Edited by admin on Sat Dec 16 11:38:00 GMT 2023

PRIMARY

FDA UNII

RJF24P5QDS

Created by admin on Sat Dec 16 11:38:00 GMT 2023 , Edited by admin on Sat Dec 16 11:38:00 GMT 2023

PRIMARY

MANUFACTURER PRODUCT INFORMATION

TAK-778

Created by admin on Sat Dec 16 11:38:00 GMT 2023 , Edited by admin on Sat Dec 16 11:38:00 GMT 2023

PRIMARY

This trial will investigate the long-term safety and tolerability of TAK 875 in Japanese patients ... Double-blind Comparative Study of TAK-875. ... 800-778-2860

Related Record Type Details


					RJF24P5QDS

TAK-778

ACTIVE MOIETY