Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C30H37N3O7S |
| Molecular Weight | 583.696 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(NS(C)(=O)=O)C=C(C=C1NC(=O)C(=O)C2=C3C=CC=CC3=C(OCCN4CCOCC4)C=C2)C(C)(C)C
InChI
InChIKey=UUROSJLZNDSXRF-UHFFFAOYSA-N
InChI=1S/C30H37N3O7S/c1-30(2,3)20-18-24(28(38-4)25(19-20)32-41(5,36)37)31-29(35)27(34)23-10-11-26(22-9-7-6-8-21(22)23)40-17-14-33-12-15-39-16-13-33/h6-11,18-19,32H,12-17H2,1-5H3,(H,31,35)
| Molecular Formula | C30H37N3O7S |
| Molecular Weight | 583.696 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Evaluation of ITX 5061, a scavenger receptor B1 antagonist: resistance selection and activity in combination with other hepatitis C virus antivirals. | 2012-02-15 |
|
| Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors. | 2011-01 |
|
| Targeting HCV entry for development of therapeutics. | 2010-08 |
|
| Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor. | 2009-12 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:18:31 GMT 2025
by
admin
on
Mon Mar 31 21:18:31 GMT 2025
|
| Record UNII |
RDD1D7O9YX
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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848144-15-0
Created by
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11786594
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admin on Mon Mar 31 21:18:31 GMT 2025 , Edited by admin on Mon Mar 31 21:18:31 GMT 2025
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RDD1D7O9YX
Created by
admin on Mon Mar 31 21:18:31 GMT 2025 , Edited by admin on Mon Mar 31 21:18:31 GMT 2025
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DTXSID00233876
Created by
admin on Mon Mar 31 21:18:31 GMT 2025 , Edited by admin on Mon Mar 31 21:18:31 GMT 2025
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PRIMARY |
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SALT/SOLVATE -> PARENT |
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TARGET -> INHIBITOR |
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ACTIVE MOIETY |
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