PENTIAPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H17N5S
Molecular Weight	299.394
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCN(CC1)C2=NC3=C(SC4=NC=CN24)C=CC=C3

InChI

InChIKey=FACMWMBWGSPRKO-UHFFFAOYSA-N

InChI=1S/C15H17N5S/c1-18-8-10-19(11-9-18)14-17-12-4-2-3-5-13(12)21-15-16-6-7-20(14)15/h2-7H,8-11H2,1H3

HIDE SMILES / InChI

Molecular Formula	C15H17N5S
Molecular Weight	299.394
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/11704248 | https://www.ncbi.nlm.nih.gov/pubmed/9443558 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 948, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Pentiapine is a dopamine release inhibitor. It is a tranquiliser. Pentiapine produces a dose-dependent decrease in spontaneous motor activity and blocks the morphineinduced hyperactivity. Moreover, this drug in itself has no effect on place conditioning but blocks the acquisition of morphine-induced conditioned place preference.

Approval Year

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

24 and 32 mg/kg

Route of Administration: Intraperitoneal

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:36:52 GMT 2023` Edited by `admin` on `Fri Dec 15 16:36:52 GMT 2023`
Record UNII	RAP39VD6P5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PENTIAPINE

Official Name

English

5-(4-METHYL-1-PIPERAZINYL)IMIDAZO(2,1-B)(1,3,5)BENZOTHIADIAZEPINE

Systematic Name

English

pentiapine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66883