SKF-38393

OC1=C(O)C=C2C(CNCCC2=C1)C3=CC=CC=C3

InChIKey=JUDKOGFHZYMDMF-UHFFFAOYSA-N

InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine D1 receptor 106 Target ID: CHEMBL2056 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6427836 \| https://www.ncbi.nlm.nih.gov/pubmed/3110837 \| https://www.ncbi.nlm.nih.gov/pubmed/25308766 \| https://www.ncbi.nlm.nih.gov/pubmed/8307098	Partial Agonist 297		130.0 nM [EC50]
Dopamine D5 receptor 15 Target ID: CHEMBL1850 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1826762	Partial Agonist 297		100.0 nM [Ki]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:50:56 GMT 2025` Edited by `admin` on `Mon Mar 31 17:50:56 GMT 2025`
Record UNII	R7TF327S2C
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

SKF-38393, (±)-

Preferred Name

English

SKF-38393

Code

English

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE

Systematic Name

English

2,3,4,5-TETRAHYDRO-1-PHENYL-1H-3-BENZAZEPINE-7,8-DIOL

Systematic Name

English

1H-3-BENZAZEPINE-7,8-DIOL, 2,3,4,5-TETRAHYDRO-1-PHENYL-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID10894836