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Details

Stereochemistry RACEMIC
Molecular Formula C28H41N3O3
Molecular Weight 467.6434
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIROPRAMIDE

SMILES

CCCN(CCC)C(=O)C(CC1=CC=C(OCCN(CC)CC)C=C1)NC(=O)C2=CC=CC=C2

InChI

InChIKey=FDBWMYOFXWMGEY-UHFFFAOYSA-N
InChI=1S/C28H41N3O3/c1-5-18-31(19-6-2)28(33)26(29-27(32)24-12-10-9-11-13-24)22-23-14-16-25(17-15-23)34-21-20-30(7-3)8-4/h9-17,26H,5-8,18-22H2,1-4H3,(H,29,32)

HIDE SMILES / InChI

Molecular Formula C28H41N3O3
Molecular Weight 467.6434
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Tiropramide is an antispasmodic medication. It acts by increasing cAMP concentration in smooth muscle possibly because of inhibition of cAMP catabolism. The drug is marketed worldwide for the treatment of irritable bowel syndrome, biliary dyskinesia, acute spasmodic dysphoric syndromes, and other urological and gynecological disorders.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
19.0 µM [IC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
ALFOSPAS

PubMed

Substance Class Chemical
Record UNII
R7S0904CN2
Record Status Validated (UNII)
Record Version