U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ACHIRAL
Molecular Formula C10H12N4O2S2
Molecular Weight 284.358
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFAETHIDOLE

SMILES

CCC1=NN=C(NS(=O)(=O)C2=CC=C(N)C=C2)S1

InChI

InChIKey=SVYBEBLNQGDRHF-UHFFFAOYSA-N
InChI=1S/C10H12N4O2S2/c1-2-9-12-13-10(17-9)14-18(15,16)8-5-3-7(11)4-6-8/h3-6H,2,11H2,1H3,(H,13,14)

HIDE SMILES / InChI
Molecular Formula C10H12N4O2S2
Molecular Weight 284.358
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Sulfaethidole is an antibacterial agent, indicated for the treatment of urinary tract infection.

Originator

Smith Kline & French Laboratories
21

Approval Year

1956
94

Conditions

ConditionModalityTargetsHighest PhaseProduct
Urinary tract infections
207
 Curative
Approved
8,583
Sul-Spansion

Cmax

ValueDoseCo-administeredAnalytePopulation
125 μg/mL
1 g single, oral
DICLOXACILLIN
 SULFAETHIDOLE serum
Homo sapiens

Funbound

ValueDoseCo-administeredAnalytePopulation
2.5%
SULFAETHIDOLE plasma
Homo sapiens

PubMed

Patents

US9016221
15
US9775802
2

Sample Use Guides

In Vivo Use Guide
Urinary tract infections Adult: 1.5-4 g/day in 3-4 divided doses. Child: 30-45 mg/kg/day in 4 divided doses.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
R77Q4O5ZMD
Record Status Validated (UNII)
Record Version
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966