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Details

Stereochemistry ACHIRAL
Molecular Formula C10H7O3S.Na
Molecular Weight 230.216
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM 2-NAPHTHALENESULFONATE

SMILES

[Na+].[O-]S(=O)(=O)C1=CC=C2C=CC=CC2=C1

InChI

InChIKey=YWPOLRBWRRKLMW-UHFFFAOYSA-M
InChI=1S/C10H8O3S.Na/c11-14(12,13)10-6-5-8-3-1-2-4-9(8)7-10;/h1-7H,(H,11,12,13);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C10H7O3S
Molecular Weight 207.226
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sodium 2-naphthalenesulfonate is a sodium salt of naphthalene sulfonic acid. Sodium 2-naphthalenesulfonate is a surfactant-hydrotrope used in cosmetics. Use concentrations would be typically below 2%. In clinical studies, Sodium 2-naphthalenesulfonate was neither an irritant (tested up to 2%), cumulative irritant (tested up to 1%), nor a sensitizer (tested up to 1%). Sodium 2-naphthalenesulfonate is considered safe as used in cosmetic formulations intended to be applied to the skin.

Approval Year

PubMed

PubMed

TitleDatePubMed
Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.
2010-08-24
Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile.
2010-08-19
Preparation of poly(1,5 diamino naphthalene) nanobelts/nanodiscs through a "hard-soft combined templates" approach.
2010-08
The development of electrically conductive polycaprolactone fumarate-polypyrrole composite materials for nerve regeneration.
2010-08
Structure, morphology, and bioactivity of biocompatible systems derived from functionalized acrylic polymers based on 5-amino-2-naphthalene sulfonic acid.
2010-07-12
Microbial conversion of 5-sulfoisophthalic acid into 5-hydroxyisophthalic acid by Ochrobactrum anthropi S9.
2010-03
Rich aggregate morphologies induced by organic salts in aqueous solutions of a cationic gemini surfactant with a short spacer.
2009-12-01
Experiments on moving interaction boundaries and their characteristics of focusing and probing of both guest and host target molecules.
2009-09-14
Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs.
2009-07-01
The role of cross-linking structures to the formation of one-dimensional nano-organized polyaniline and their Raman fingerprint.
2008-12-01
Photochemical elimination of leaving groups from zwitterionic intermediates generated via electrocyclic ring closure of alpha,beta-unsaturated anilides.
2008-11-21
Influence of anionic sulfonate-containing co-ligands on the solid structures of silver complexes supported by 4,4'-bipyridine bridges.
2008-10-21
Efficient removal of aromatic sulfonates from wastewater by a recyclable polymer: 2-naphthalene sulfonate as a representative pollutant.
2008-10-01
trans-Diaqua-bis(ethyl-enediamine-κN,N')copper(II) bis[3-(3-pyrid-yl)propionate] dihydrate.
2008-03-05
Heterogeneity of the adsorption mechanism of low molecular weight compounds in reversed-phase liquid chromatography.
2006-08-15
Nanostructuring of poly(diphenylamine) inside the galleries of montmorillonite organo clay through self-assembly approach.
2006-06
Adsorption mechanism in reversed-phase liquid chromatography. Effect of the surface coverage of a monomeric C18-silica stationary phase.
2006-05-19
Measurement of monomolecular binding constants of neutral phenols into the beta-cyclodextrin by continuous frontal analysis in capillary and microchip electrophoresis via a competitive assay.
2006-02-03
Treatment of naphthalene-2-sulfonic acid from tannery wastewater by a granular activated carbon fixed bed inoculated with bacterial isolates Arthrobacter globiformis and Comamonas testosteroni.
2006-02
A chromatographic estimate of the degree of surface heterogeneity of RPLC packing materials. III. Endcapped amido-embedded reversed phase.
2006-01-20
A chromatographic estimate of the degree of heterogeneity of RPLC packing materials. 1. Non-endcapped polymeric C30-bonded stationary phase.
2006-01-20
Depolymerisation and biodegradation of a synthetic tanning agent by activated sludges, the bacteria Arthrobacter globiformis and Comamonas testosteroni, and the fungus Cunninghamella polymorpha.
2005-08
Biodegradation of naphthalene-2-sulfonic acid present in tannery wastewater by bacterial isolates Arthrobacter sp. 2AC and Comamonas sp. 4BC.
2005-06
Sorption enhancement of aromatic sulfonates onto an aminated hyper-cross-linked polymer.
2005-05-01
Temperature-induced sedimentation to dispersion of ionic vesicles.
2005-04-01
Decomposition of 2-naphthalenesulfonate in electroplating solution by ozonation with UV radiation.
2005-02-14
Adsorption of beta-naphthalenesulfonic acid/sulfuric acid from their solution by weakly basic resin: equilibrium.
2005
Silver(I) arylsulfonates: a systematic study of "softer" hybrid inorganic-organic solids.
2004-10-18
Separation and migration behavior of positional and structural naphthalenesulfonate isomers by cyclodextrin-mediated capillary electrophoresis.
2004-04-09
Analysis of a retan agent used in the tanning process and its determination in tannery wastewater.
2003-03-15
The determination of a potential impurity in Thalidomide drug substance and product by HPLC with indirect UV detection.
2003-02-05
Electrochemical synthesis of novel polypyrrole microstructures.
2003-01-21
Final report on the amended safety assessment of sodium polynaphthalenesulfonate and sodium naphthalenesulfonate.
2003
Decomposition of 2-naphthalenesulfonate in aqueous solution by ozonation with UV radiation.
2002-09
Isotachophoretic focusing and mass spectrometry detection as tools for improving the determination of aromatic sulfonates in capillary electrophoresis.
2002-07
Amplification of small analytes in polymer solution by capillary electrophoresis.
2002-06
Stability study and determination of benzene- and naphthalenesulfonates following an on-line solid-phase extraction method using the new programmable field extraction system.
2002-04
Dendritic galactosides based on a beta-cyclodextrin core for the construction of site-specific molecular delivery systems: synthesis and molecular recognition studies.
2002-02-15
Development of generic liquid chromatography-mass spectrometry methods using experimental design.
2002-01
Investigation of naphtalene sulfonate compounds sorption in a soil artificially contaminated using batch and column assays.
2002
Binding affinity properties of dendritic glycosides based on a beta-cyclodextrin core toward guest molecules and concanavalin A.
2001-11-16
Determination of naphthalenesulfonic acid isomers by large-volume on-line derivatization and gas chromatography-mass spectrometry.
2001-08-17
Determination of cyclodextrins and their derivatives by capillary electrophoresis with indirect UV and conductivity detection.
2001-04
Protonation effects on the inclusion complexation of 6-deoxy-6-diethylamino-beta-cyclodextrin with 2-anthracenesulfonate, 2-naphthalenesulfonate, 2,6-naphthalenedisulfonate, and 2,7-naphthalenedisulfonate in aqueous solutions.
2001-01
Patents

Sample Use Guides

In clinical studies, Sodium 2-naphthalenesulfonate was neither an irritant (tested up to 2%), cumulative irritant (tested up to 1%), nor a sensitizer (tested up to 1%).
Route of Administration: Topical
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:55:15 GMT 2025
Edited
by admin
on Mon Mar 31 17:55:15 GMT 2025
Record UNII
R5F0CTD2OJ
Record Status Validated (UNII)
Record Version
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Name Type Language
SODIUM 2-NAPHTHALENESULFONATE
II  
Systematic Name English
NSA
Preferred Name English
SODIUM .BETA.-NAPHTHALENESULFONATE
Systematic Name English
SODIUM NAPHTHALENE-6-SULPHONATE
Systematic Name English
NSC-7415
Code English
SODIUM 2-NAPHTHALENESULFONATE [II]
Common Name English
2-NAPHTHALENESULFONATE
Common Name English
SODIUM 2-NAPHTHALENESULPHONATE
Systematic Name English
SODIUM .BETA.-NAPHTHALENESULPHONATE
Systematic Name English
2-NAPHTHALENESULFONIC ACID, SODIUM SALT (1:1)
Common Name English
SODIUM NAPHTHALENE-2-SULPHONATE
Systematic Name English
SODIUM NAPHTHALENE-6-SULFONATE
Systematic Name English
2-NAPHTHALENESULFONIC ACID, SODIUM SALT
Common Name English
.BETA.-NAPHTHALENESULFONIC ACID SODIUM SALT
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 217202
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
Code System Code Type Description
EPA CompTox
DTXSID4041442
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
FDA UNII
R5F0CTD2OJ
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
CAS
532-02-5
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
DAILYMED
R5F0CTD2OJ
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
RXCUI
1366947
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
ALTERNATIVE
ECHA (EC/EINECS)
208-523-8
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
CHEBI
25476
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
PUBCHEM
23661868
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
NSC
7415
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY
RXCUI
1366946
Created by admin on Mon Mar 31 17:55:15 GMT 2025 , Edited by admin on Mon Mar 31 17:55:15 GMT 2025
PRIMARY RxNorm
Related Record Type Details
PARENT -> SALT/SOLVATE