2-NAPHTHALENESULFONIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H8O3S
Molecular Weight	208.234
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(=O)(=O)C1=CC=C2C=CC=CC2=C1

InChI

InChIKey=KVBGVZZKJNLNJU-UHFFFAOYSA-N

InChI=1S/C10H8O3S/c11-14(12,13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H,11,12,13)

HIDE SMILES / InChI

Molecular Formula	C10H8O3S
Molecular Weight	208.234
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ewg.org/skindeep/ingredient/723830/SODIUM_NAPHTHALENESULFONATE/ | https://www.ncbi.nlm.nih.gov/pubmed/14555418 | http://www.thegoodscentscompany.com/data/rw1179321.html

Sodium 2-naphthalenesulfonate is a sodium salt of naphthalene sulfonic acid. Sodium 2-naphthalenesulfonate is a surfactant-hydrotrope used in cosmetics. Use concentrations would be typically below 2%. In clinical studies, Sodium 2-naphthalenesulfonate was neither an irritant (tested up to 2%), cumulative irritant (tested up to 1%), nor a sensitizer (tested up to 1%). Sodium 2-naphthalenesulfonate is considered safe as used in cosmetic formulations intended to be applied to the skin.

Approval Year

PubMed

Title	Date	PubMed
Determination of cyclodextrins and their derivatives by capillary electrophoresis with indirect UV and conductivity detection.	2001 Apr	11371069
Protonation effects on the inclusion complexation of 6-deoxy-6-diethylamino-beta-cyclodextrin with 2-anthracenesulfonate, 2-naphthalenesulfonate, 2,6-naphthalenedisulfonate, and 2,7-naphthalenedisulfonate in aqueous solutions.	2001 Jan	11209851
Investigation of naphtalene sulfonate compounds sorption in a soil artificially contaminated using batch and column assays.	2002	12423058
Stability study and determination of benzene- and naphthalenesulfonates following an on-line solid-phase extraction method using the new programmable field extraction system.	2002 Apr	12022643
Dendritic galactosides based on a beta-cyclodextrin core for the construction of site-specific molecular delivery systems: synthesis and molecular recognition studies.	2002 Feb 15	11857696
Development of generic liquid chromatography-mass spectrometry methods using experimental design.	2002 Jan	11777196
Isotachophoretic focusing and mass spectrometry detection as tools for improving the determination of aromatic sulfonates in capillary electrophoresis.	2002 Jul	12210234
Amplification of small analytes in polymer solution by capillary electrophoresis.	2002 Jun	12179982
Decomposition of 2-naphthalenesulfonate in aqueous solution by ozonation with UV radiation.	2002 Sep	12405423
Final report on the amended safety assessment of sodium polynaphthalenesulfonate and sodium naphthalenesulfonate.	2003	14555418
The determination of a potential impurity in Thalidomide drug substance and product by HPLC with indirect UV detection.	2003 Feb 5	12560045
Electrochemical synthesis of novel polypyrrole microstructures.	2003 Jan 21	12585393
Analysis of a retan agent used in the tanning process and its determination in tannery wastewater.	2003 Mar 15	12659187
Separation and migration behavior of positional and structural naphthalenesulfonate isomers by cyclodextrin-mediated capillary electrophoresis.	2004 Apr 9	15072302
Silver(I) arylsulfonates: a systematic study of "softer" hybrid inorganic-organic solids.	2004 Oct 18	15476366
Adsorption of beta-naphthalenesulfonic acid/sulfuric acid from their solution by weakly basic resin: equilibrium.	2005	16158597
Temperature-induced sedimentation to dispersion of ionic vesicles.	2005 Apr 1	15752823
Depolymerisation and biodegradation of a synthetic tanning agent by activated sludges, the bacteria Arthrobacter globiformis and Comamonas testosteroni, and the fungus Cunninghamella polymorpha.	2005 Aug	15865336
Decomposition of 2-naphthalenesulfonate in electroplating solution by ozonation with UV radiation.	2005 Feb 14	15721542
Biodegradation of naphthalene-2-sulfonic acid present in tannery wastewater by bacterial isolates Arthrobacter sp. 2AC and Comamonas sp. 4BC.	2005 Jun	15865148
Sorption enhancement of aromatic sulfonates onto an aminated hyper-cross-linked polymer.	2005 May 1	15926583
Heterogeneity of the adsorption mechanism of low molecular weight compounds in reversed-phase liquid chromatography.	2006 Aug 15	16906729
Treatment of naphthalene-2-sulfonic acid from tannery wastewater by a granular activated carbon fixed bed inoculated with bacterial isolates Arthrobacter globiformis and Comamonas testosteroni.	2006 Feb	16427119
Measurement of monomolecular binding constants of neutral phenols into the beta-cyclodextrin by continuous frontal analysis in capillary and microchip electrophoresis via a competitive assay.	2006 Feb 3	16376902
A chromatographic estimate of the degree of heterogeneity of RPLC packing materials. 1. Non-endcapped polymeric C30-bonded stationary phase.	2006 Jan 20	16337638
Nanostructuring of poly(diphenylamine) inside the galleries of montmorillonite organo clay through self-assembly approach.	2006 Jun	17025057
Adsorption mechanism in reversed-phase liquid chromatography. Effect of the surface coverage of a monomeric C18-silica stationary phase.	2006 May 19	16580678
The role of cross-linking structures to the formation of one-dimensional nano-organized polyaniline and their Raman fingerprint.	2008 Dec 1	18343714
trans-Diaqua-bis(ethyl-enediamine-κN,N')copper(II) bis[3-(3-pyrid-yl)propionate] dihydrate.	2008 Mar 5	21201981
Rich aggregate morphologies induced by organic salts in aqueous solutions of a cationic gemini surfactant with a short spacer.	2009 Dec 1	19762036
Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs.	2009 Jul 1	19264104
Experiments on moving interaction boundaries and their characteristics of focusing and probing of both guest and host target molecules.	2009 Sep 14	19720181
Preparation of poly(1,5 diamino naphthalene) nanobelts/nanodiscs through a "hard-soft combined templates" approach.	2010 Aug	21125886
The development of electrically conductive polycaprolactone fumarate-polypyrrole composite materials for nerve regeneration.	2010 Aug	20483452
Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile.	2010 Aug 19	20808849
Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.	2010 Aug 24	20808768
Structure, morphology, and bioactivity of biocompatible systems derived from functionalized acrylic polymers based on 5-amino-2-naphthalene sulfonic acid.	2010 Jul 12	20527810
Microbial conversion of 5-sulfoisophthalic acid into 5-hydroxyisophthalic acid by Ochrobactrum anthropi S9.	2010 Mar	19941033

Patents

Sample Use Guides

In Vivo Use Guide

In clinical studies, Sodium 2-naphthalenesulfonate was neither an irritant (tested up to 2%), cumulative irritant (tested up to 1%), nor a sensitizer (tested up to 1%).

Route of Administration: Topical

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:38:05 GMT 2023` Edited by `admin` on `Fri Dec 15 18:38:05 GMT 2023`
Record UNII	O9S4K2S25E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-NAPHTHALENESULFONIC ACID

Systematic Name

English

NAPHTHALENE-2-SULPHONIC ACID

Systematic Name

English

.BETA.-NAPHTHALENESULFONIC ACID

Systematic Name

English

NAPHTHALENE-2-SULFONIC ACID

Systematic Name

English

2-NAPHTHALENESULFONIC ACID, MONOHYDRATE

Common Name

English

2-NAPHTHALENESULFONIC ACID [MI]

Common Name

English

Code System Code Type Description

CAS

120-18-3