PEGLOTICASE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:56:10 GMT 2025` Edited by `admin` on `Wed Apr 02 01:56:10 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	PIG
Sequence Type	COMPLETE
Record UNII	R581OT55EA
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

KRYSTEXXA

Preferred Name

English

PEGLOTICASE

Official Name

English

PEGLOTICASE [MI]

Common Name

English

PEGLOTICASE [PURPLE BOOK CDER]

Common Name

English

PEGLOTICASE [MART.]

Common Name

English

PEGLOTICASE [USAN]

Common Name

English

Pegloticase [WHO-DD]

Common Name

English

pegloticase [INN]

Common Name

English

PEGLOTICASE [VANDF]

Common Name

English

PURICASE

Brand Name

English

OXIDASE, URATE (SYNTHETIC SUS SCROFA VARIANT PIGKS-DN SUBUNIT), HOMOTETRAMER, AMIDE WITH .ALPHA.-CARBOXY-.OMEGA.-METHOXYPOLY(OXY-1,2-ETHANEDIYL)

Common Name

English

DES-(1-6)-(7-THREONINE,46-THREONINE,291-LYSINE,301-SERINE)URICASE (EC 1.7.3.3, URATE OXIDASE) SUS SCROFA (PIG) TETRAMER, NON ACETYLATED, CARBAMATES WITH .ALPHA.-CARBOXY-.OMEGA.-METHOXYPOLY(OXYETHYLENE)

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175670

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

LIVERTOX

NBK548768

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

FDA ORPHAN DRUG

135600

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

WHO-VATC

QM04AX02

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

NCI_THESAURUS

C921

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

WHO-ATC

M04AX02

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

EMA ASSESSMENT REPORTS

KRYSTEXXA (AUTHORIZED: GOUT)

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

Code System Code Type Description

ChEMBL

CHEMBL1237025

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

RXCUI

1011650

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

RxNorm

DAILYMED

R581OT55EA

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

IUPHAR

7463

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

SMS_ID

100000124526

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

USAN

XX-121

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

EVMPD

SUB32159

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

INN

8934

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

NCI_THESAURUS

C97466

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

FDA UNII

R581OT55EA

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

DRUG CENTRAL

5176

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

CAS

885051-90-1

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

MERCK INDEX

m8447

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

Merck Index

WIKIPEDIA

PEGLOTICASE

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

DRUG BANK

DB09208

Created by admin on Wed Apr 02 01:56:10 GMT 2025 , Edited by admin on Wed Apr 02 01:56:10 GMT 2025

PRIMARY

Related Record Type Details


					268B43MJ25

URIC ACID

SUBSTRATE->ENZYME

Amount:

Related Record Type Details


					R581OT55EA

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		SITE_SPECIFIC	K	Amount:	UNSPECIFIED SUBSTANCE	9f283784 (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Biological Half-life	PHARMACOKINETIC				Elimination PHARMACOKINETIC

Molecular Formula	CHEMICAL