SODIUM TARTRATE

US Approved OTC

First marketed in 1921

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C4H4O6.2Na
Molecular Weight	194.0505
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Na+].O[C@H]([C@@H](O)C([O-])=O)C([O-])=O

InChI

InChIKey=HELHAJAZNSDZJO-OLXYHTOASA-L

InChI=1S/C4H6O6.2Na/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);;/q;2*+1/p-2/t1-,2-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H4O6
Molecular Weight	148.071
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://link.springer.com/article/10.1007/s12045-007-0005-6 | http://www.foodchemadditives.com/products/L-Tartaric-Acid

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
skin cleasing 8 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a33a11b2-926e-43bb-8775-d94b730d2c78	Inactive ingredient		Approved 8429	CLEARASIL DAILY CLEAR CLEAR SKIN Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
3B Scientific (Wuhan) Corp	3B3-059382	http://www.3bsc.com/index/pro_info.php?id=98203
AK Scientific, Inc. (AKSCI)	7165AF	http://www.aksci.com/item_detail.php?cat=7165AF
Acadechem	ACDS-067423	http://www.acadechemical.com/product/142122
Alfa Chemistry	AP6106247-A	https://reagents.alfa-chemistry.com/product/sodium-tartrate-dihydrate-cas-6106-24-7-14010.html
Alfa Chemistry	AP6106247-B	https://reagents.alfa-chemistry.com/product/sodium-tartrate-dihydrate-cas-6106-24-7-14011.html
Ambinter	Amb22348226	http://www.ambinter.com/reference/22348226
Anward	ANW-33667	http://www.anward.com/pro_result/23235
Aurora Fine Chemicals LLC	A14.518.215	http://online.aurorafinechemicals.com/info?ID=A14.518.215
Avantor Inc	101225-558	https://us.vwr.com/store/catalog/product.jsp?catalog_number=101225-558
Avantor Inc	101226-150	https://us.vwr.com/store/catalog/product.jsp?catalog_number=101226-150
BOC Sciences	6106-24-7	https://www.bocsci.com/disodium-tartrate-dihydrate-cas-6106-24-7-item-95530.html
Chemspace	CSSB00102632354	https://chem-space.com/CSSB00102632354
Combi-Blocks	QE-8461	http://www.combi-blocks.com/cgi-bin/find.cgi?QE-8461
Fisher Chemical	AL2770100	https://www.fishersci.com/shop/products/aqualine-sodium-tartrate-dihydrate-water-standard-fisher-chemical/AL2770100
Fisher Chemical	S433100	https://www.fishersci.com/shop/products/sodium-l-tartrate-dihydrate-crystalline-certified-fisher-chemical-2/p-192917
Fisher Chemical	S433500	https://www.fishersci.com/shop/products/sodium-l-tartrate-dihydrate-crystalline-certified-fisher-chemical-2/p-192917
Glentham Life Sciences	GK1687	http://www.glentham.com/products/product/GK1687/
MolPort	MolPort-003-928-192	https://www.molport.com/shop/molecule-link/MolPort-003-928-192
Oakwood	104960	http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=196368&ExtHyperLink=1
Oakwood	94747	http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=79921&ExtHyperLink=1
Sigma-Aldrich	28-4380_SAJ	https://www.sigmaaldrich.com/catalog/product/saj/284380?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	228729_SIAL	https://www.sigmaaldrich.com/catalog/product/sial/228729?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	71995_SIAL	https://www.sigmaaldrich.com/catalog/product/sial/71995?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	71994_SIGMA	https://www.sigmaaldrich.com/catalog/product/sigma/71994?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	1614909_USP	https://www.sigmaaldrich.com/catalog/product/usp/1614909?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sinfoo Biotech	S051766	http://www.sinfoobiotech.com/product/1055164
abcr GmbH	AB118837	http://www.abcr.de/shop/en/AB118837
abcr GmbH	AB207455	http://www.abcr.de/shop/en/AB207455
iChemical	EBD16533	http://www.ichemical.com/chemicals/cas-6106-24-7

PubMed

Title	Date	PubMed
Synthesis and evaluation of a C-glycosyl nucleoside as an inhibitor of chitin synthase.	2001 Aug 30	11513824
Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase.	2001 Dec	11733005
A comparison of salts for the crystallization of macromolecules.	2001 Feb	11266627
Sarcosinium tartrate.	2001 Feb	11173439
Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin.	2001 Jan	11464877
Comparison of the clinical success and quality-of-life impact of brimonidine 0.2% and betaxolol 0.25 % suspension in patients with elevated intraocular pressure.	2001 Jul	11519768
Malo-ethanolic fermentation in grape must by recombinant strains of Saccharomyces cerevisiae.	2001 Jul	11447602
Isolation and characterization of Mn(III) tartrate from Phanerochaete chrysosporium culture broth.	2001 Jul 24	11470372
Determination of organic acids of low molecular weight and phosphate in soil by capillary electrophoresis.	2001 Jul-Aug	11501905
Catalytic spectrophotometric determination of vanadium in seawaters based on the bromate oxidative coupling reaction of metol and 2,3,4-trihydroxybenzoic acid.	2001 Jun	11707949
Chiral separations of transition metal complexes using capillary zone electrophoresis.	2001 Jun 15	11442050
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport.	2001 May 11	11278867
[Acid phosphatase, ACP (EC 3.1.3.2)].	2001 Nov	11797369
Technetium-99m direct radiolabeling of lanreotide: a somatostatin analog.	2001 Nov	11573798
Novel bicistronic retroviral vector expressing gamma-glutamylcysteine synthetase and the multidrug resistance protein 1 (MRP1) protects cells from MRP1-effluxed drugs and alkylating agents.	2001 Sep 20	11560771
Preformulation studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability.	2002	11926357
The MRP1-mediated effluxes of arsenic and antimony do not require arsenic-glutathione and antimony-glutathione complex formation.	2002 Apr	12018890
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.	2002 Apr	11937054
Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis.	2002 Apr 18	11950362
Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature.	2002 Aug 1	12112683
Thermophysical properties of pharmaceutically compatible buffers at sub-zero temperatures: implications for freeze-drying.	2002 Feb	11883647
Ergotamine-induced anorectal strictures: report of five cases.	2002 Feb	11852344
Revision of absolute configuration of enantiomeric (methylenecyclopropyl)carbinols obtained from (R)-(-)- and (S)-(+)-epichlorohydrin and methylenetriphenylphosphorane. Implications for reaction mechanism and improved synthesis of antiviral methylenecyclopropane analogues of nucleosides.	2002 Jan 11	11777473
Effect of antibiotics on in vitro and in vivo avian cartilage degradation.	2002 Jan-Mar	11922351
Improving the labeling of S-acetyl NHS-MAG(3)-conjugated morpholino oligomers.	2002 Jul-Aug	12121147
Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice.	2002 Jun	12054176
Consumption of an omega-3 fatty acids product, INCELL AAFA, reduced side-effects of CPT-11 (irinotecan) in mice.	2002 Mar 18	11953833
Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells.	2002 May	11956606
Formation of methylantimony species by an aerobic prokaryote: Flavobacterium sp.	2002 Oct	12209260
Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5.	2002 Oct 15	12119043
Symmetric and helical growth of polyacetylene fibers over a single copper crystal derived from copper tartrate decomposition.	2002 Sep 5	12201732

Patents

Sample Use Guides

In Vivo Use Guide

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg

Route of Administration: Oral

In Vitro Use Guide

After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:10:24 GMT 2023` Edited by `admin` on `Fri Dec 15 15:10:24 GMT 2023`
Record UNII	QTO9JB4MDD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SODIUM TARTRATE

Systematic Name

English

DISODIUM L-TARTRATE

Systematic Name

English

SODIUM TARTRATE [MI]

Common Name

English

INS-335(II)

Code

English

DISODIUM TARTRATE [INCI]

Common Name

English

SODIUM DEXTRO-TARTRATE

Common Name

English

BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, DISODIUM SALT

Common Name

English

SODIUM TARTRATE [FCC]

Common Name

English

SODIUM (+)-TARTRATE

Systematic Name

English

Sodium tartrate [WHO-DD]

Common Name

English

E-335(II)

Code

English

DISODIUM (+)-2,3-DIHYDROXYBUTANEDIOIC ACID

Systematic Name

English

DISODIUM TARTRATE

Official Name

English

INS NO.335(II)

Code

English

SODIUM TARTRATE, L (+)-

Common Name

English

SODIUM TARTRATE [MART.]

Common Name

English

TARTARIC ACID, DISODIUM SALT

Common Name

English

SODIUM TARTRATE [II]

Common Name

English

Classification Tree Code System Code

JECFA EVALUATION

INS-335(II)