SODIUM TARTRATE

US Approved OTC

First marketed in 1921

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C4H4O6.2Na
Molecular Weight	194.0505
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Na+].O[C@H]([C@@H](O)C([O-])=O)C([O-])=O

InChI

InChIKey=HELHAJAZNSDZJO-OLXYHTOASA-L

InChI=1S/C4H6O6.2Na/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);;/q;2*+1/p-2/t1-,2-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H4O6
Molecular Weight	148.071
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://link.springer.com/article/10.1007/s12045-007-0005-6 | http://www.foodchemadditives.com/products/L-Tartaric-Acid

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
skin cleasing 9 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a33a11b2-926e-43bb-8775-d94b730d2c78	Inactive ingredient		Approved 8360	CLEARASIL DAILY CLEAR CLEAR SKIN Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
3B Scientific (Wuhan) Corp	3B3-059382	http://www.3bsc.com/index/pro_info.php?id=98203
AK Scientific, Inc. (AKSCI)	7165AF	http://www.aksci.com/item_detail.php?cat=7165AF
Acadechem	ACDS-067423	http://www.acadechemical.com/product/142122
Alfa Chemistry	AP6106247-A	https://reagents.alfa-chemistry.com/product/sodium-tartrate-dihydrate-cas-6106-24-7-14010.html
Alfa Chemistry	AP6106247-B	https://reagents.alfa-chemistry.com/product/sodium-tartrate-dihydrate-cas-6106-24-7-14011.html
Ambinter	Amb22348226	http://www.ambinter.com/reference/22348226
Anward	ANW-33667	http://www.anward.com/pro_result/23235
Aurora Fine Chemicals LLC	A14.518.215	http://online.aurorafinechemicals.com/info?ID=A14.518.215
Avantor Inc	101225-558	https://us.vwr.com/store/catalog/product.jsp?catalog_number=101225-558
Avantor Inc	101226-150	https://us.vwr.com/store/catalog/product.jsp?catalog_number=101226-150
BOC Sciences	6106-24-7	https://www.bocsci.com/disodium-tartrate-dihydrate-cas-6106-24-7-item-95530.html
Chemspace	CSSB00102632354	https://chem-space.com/CSSB00102632354
Combi-Blocks	QE-8461	http://www.combi-blocks.com/cgi-bin/find.cgi?QE-8461
Fisher Chemical	AL2770100	https://www.fishersci.com/shop/products/aqualine-sodium-tartrate-dihydrate-water-standard-fisher-chemical/AL2770100
Fisher Chemical	S433100	https://www.fishersci.com/shop/products/sodium-l-tartrate-dihydrate-crystalline-certified-fisher-chemical-2/p-192917
Fisher Chemical	S433500	https://www.fishersci.com/shop/products/sodium-l-tartrate-dihydrate-crystalline-certified-fisher-chemical-2/p-192917
Glentham Life Sciences	GK1687	http://www.glentham.com/products/product/GK1687/
MolPort	MolPort-003-928-192	https://www.molport.com/shop/molecule-link/MolPort-003-928-192
Oakwood	104960	http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=196368&ExtHyperLink=1
Oakwood	94747	http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=79921&ExtHyperLink=1
Sigma-Aldrich	28-4380_SAJ	https://www.sigmaaldrich.com/catalog/product/saj/284380?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	228729_SIAL	https://www.sigmaaldrich.com/catalog/product/sial/228729?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	71995_SIAL	https://www.sigmaaldrich.com/catalog/product/sial/71995?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	71994_SIGMA	https://www.sigmaaldrich.com/catalog/product/sigma/71994?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	1614909_USP	https://www.sigmaaldrich.com/catalog/product/usp/1614909?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sinfoo Biotech	S051766	http://www.sinfoobiotech.com/product/1055164
abcr GmbH	AB118837	http://www.abcr.de/shop/en/AB118837
abcr GmbH	AB207455	http://www.abcr.de/shop/en/AB207455
iChemical	EBD16533	http://www.ichemical.com/chemicals/cas-6106-24-7

PubMed

Title	Date	PubMed
Inhibition of leukotriene function can modulate particulate-induced changes in bone cell differentiation and activity.	2001	11410899
Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase.	2001 Dec	11733005
Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase.	2001 Feb	11173489
Sarcosinium tartrate.	2001 Feb	11173439
A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence.	2001 Jul 1	11414680
Determination of organic acids of low molecular weight and phosphate in soil by capillary electrophoresis.	2001 Jul-Aug	11501905
Solving a 300 kDa multimeric protein by low-resolution MAD phasing and averaging/phase extension.	2001 Jun	11375499
Diverging respiratory effects of serotonin and nicotine in vagotomised cats prior to and after section of carotid sinus nerves.	2001 Mar	11321514
Classification of Ralstonia pickettii biovar 3/'thomasii' strains (Pickett 1994) and of new isolates related to nosocomial recurrent meningitis as Ralstonia mannitolytica sp. nov.	2001 Mar	11321101
[Increasing number of Salmonella paratyphi B isolates from slaughtered poultry sent in to the national Salmonella reference laboratory].	2001 May-Jun	11413710
Synthesis, characterization, and labeling with 99mTc/188Re of peptide conjugates containing a dithia-bisphosphine chelating agent.	2001 May-Jun	11353532
[Acid phosphatase, ACP (EC 3.1.3.2)].	2001 Nov	11797369
The hygroscopic properties of dicarboxylic and multifunctional acids: measurements and UNIFAC predictions.	2001 Nov 15	11757607
Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.	2001 Oct 12	11695859
Preformulation studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability.	2002	11926357
The MRP1-mediated effluxes of arsenic and antimony do not require arsenic-glutathione and antimony-glutathione complex formation.	2002 Apr	12018890
New materials for ESR dosimetry.	2002 Apr	11993477
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.	2002 Apr	11937054
Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis.	2002 Apr 18	11950362
The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.	2002 Feb	11818452
From local adsorption stresses to chiral surfaces: (R,R)-tartaric acid on Ni(110).	2002 Jan 23	11792223
In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina.	2002 Jan-Mar	11922338
High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library.	2002 Jul 18	12123528
Boronic acid receptors for alpha-hydroxycarboxylates: high affinity of Shinkai's glucose receptor for tartrate.	2002 Jul 26	12126445
Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells.	2002 May	11956606
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator.	2002 Oct 25	12171919

Patents

Sample Use Guides

In Vivo Use Guide

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg

Route of Administration: Oral

In Vitro Use Guide

After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.

Substance Class	Chemical Created by `admin` on `Wed Jul 05 22:42:04 UTC 2023` Edited by `admin` on `Wed Jul 05 22:42:04 UTC 2023`
Record UNII	QTO9JB4MDD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SODIUM TARTRATE

Systematic Name

English

DISODIUM L-TARTRATE

Systematic Name

English

SODIUM TARTRATE [MI]

Common Name

English

INS-335(II)

Code

English

DISODIUM TARTRATE [INCI]

Common Name

English

SODIUM DEXTRO-TARTRATE

Common Name

English

BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, DISODIUM SALT

Common Name

English

SODIUM TARTRATE [FCC]

Common Name

English

SODIUM (+)-TARTRATE

Systematic Name

English

Sodium tartrate [WHO-DD]

Common Name

English

E-335(II)

Code

English

DISODIUM (+)-2,3-DIHYDROXYBUTANEDIOIC ACID

Systematic Name

English

DISODIUM TARTRATE

Official Name

English

INS NO.335(II)

Code

English

SODIUM TARTRATE, L (+)-

Common Name

English

SODIUM TARTRATE [MART.]

Common Name

English

TARTARIC ACID, DISODIUM SALT

Common Name

English

SODIUM TARTRATE [II]

Common Name

English

Classification Tree Code System Code

JECFA EVALUATION

INS-335(II)