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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H4O6.2Na
Molecular Weight 194.0505
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM TARTRATE

SMILES

[Na+].[Na+].O[C@H]([C@@H](O)C([O-])=O)C([O-])=O

InChI

InChIKey=HELHAJAZNSDZJO-OLXYHTOASA-L
InChI=1S/C4H6O6.2Na/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);;/q;2*+1/p-2/t1-,2-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C4H4O6
Molecular Weight 148.071
Charge -2
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Curator's Comment: Scheele first prepared tartaric acid. Louis Pasteur discovered the existence of enantiomerism in tartaric acid

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
CLEARASIL DAILY CLEAR CLEAR SKIN

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Inhibition of leukotriene function can modulate particulate-induced changes in bone cell differentiation and activity.
2001
Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase.
2001 Dec
Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase.
2001 Feb
Sarcosinium tartrate.
2001 Feb
A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence.
2001 Jul 1
Determination of organic acids of low molecular weight and phosphate in soil by capillary electrophoresis.
2001 Jul-Aug
Solving a 300 kDa multimeric protein by low-resolution MAD phasing and averaging/phase extension.
2001 Jun
Diverging respiratory effects of serotonin and nicotine in vagotomised cats prior to and after section of carotid sinus nerves.
2001 Mar
Classification of Ralstonia pickettii biovar 3/'thomasii' strains (Pickett 1994) and of new isolates related to nosocomial recurrent meningitis as Ralstonia mannitolytica sp. nov.
2001 Mar
[Increasing number of Salmonella paratyphi B isolates from slaughtered poultry sent in to the national Salmonella reference laboratory].
2001 May-Jun
Synthesis, characterization, and labeling with 99mTc/188Re of peptide conjugates containing a dithia-bisphosphine chelating agent.
2001 May-Jun
[Acid phosphatase, ACP (EC 3.1.3.2)].
2001 Nov
The hygroscopic properties of dicarboxylic and multifunctional acids: measurements and UNIFAC predictions.
2001 Nov 15
Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.
2001 Oct 12
Preformulation studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability.
2002
The MRP1-mediated effluxes of arsenic and antimony do not require arsenic-glutathione and antimony-glutathione complex formation.
2002 Apr
New materials for ESR dosimetry.
2002 Apr
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
2002 Apr
Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis.
2002 Apr 18
The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.
2002 Feb
From local adsorption stresses to chiral surfaces: (R,R)-tartaric acid on Ni(110).
2002 Jan 23
In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina.
2002 Jan-Mar
High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library.
2002 Jul 18
Boronic acid receptors for alpha-hydroxycarboxylates: high affinity of Shinkai's glucose receptor for tartrate.
2002 Jul 26
Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells.
2002 May
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator.
2002 Oct 25
Patents

Sample Use Guides

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration: Oral
In Vitro Use Guide
After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class Chemical
Created
by admin
on Wed Jul 05 22:42:04 UTC 2023
Edited
by admin
on Wed Jul 05 22:42:04 UTC 2023
Record UNII
QTO9JB4MDD
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM TARTRATE
FCC   II   MART.   MI   WHO-DD  
Systematic Name English
DISODIUM L-TARTRATE
Systematic Name English
SODIUM TARTRATE [MI]
Common Name English
INS-335(II)
Code English
DISODIUM TARTRATE [INCI]
Common Name English
SODIUM DEXTRO-TARTRATE
Common Name English
BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, DISODIUM SALT
Common Name English
SODIUM TARTRATE [FCC]
Common Name English
SODIUM (+)-TARTRATE
Systematic Name English
Sodium tartrate [WHO-DD]
Common Name English
E-335(II)
Code English
DISODIUM (+)-2,3-DIHYDROXYBUTANEDIOIC ACID
Systematic Name English
DISODIUM TARTRATE
INCI  
INCI  
Official Name English
INS NO.335(II)
Code English
SODIUM TARTRATE, L (+)-
Common Name English
SODIUM TARTRATE [MART.]
Common Name English
TARTARIC ACID, DISODIUM SALT
Common Name English
SODIUM TARTRATE [II]
Common Name English
Classification Tree Code System Code
JECFA EVALUATION INS-335(II)
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
CFR 21 CFR 184.1801
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
CFR 21 CFR 331.11
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
WHO-VATC QA06AD21
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
WHO-ATC A06AD21
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
CFR 21 CFR 331.15
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
CODEX ALIMENTARIUS (GSFA) INS-335(II)
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
Code System Code Type Description
MERCK INDEX
M10082
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY Merck Index
RXCUI
56524
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY RxNorm
DRUG BANK
DB13707
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
EPA CompTox
DTXSID2057861
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
FDA UNII
QTO9JB4MDD
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
EVMPD
SUB15327MIG
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
SMS_ID
100000078124
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
WIKIPEDIA
SODIUM TARTRATE
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
CONCEPT Industrial Aid
DRUG CENTRAL
4780
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
JECFA MONOGRAPH
INS-335(II)
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
PUBCHEM
162637
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
ChEMBL
CHEMBL2107781
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
CAS
868-18-8
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
MESH
C029768
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
NCI_THESAURUS
C77502
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
CHEBI
63017
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
DAILYMED
QTO9JB4MDD
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
ECHA (EC/EINECS)
212-773-3
Created by admin on Wed Jul 05 22:42:05 UTC 2023 , Edited by admin on Wed Jul 05 22:42:05 UTC 2023
PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS
PARENT -> SALT/SOLVATE