SULFANITRAN

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H13N3O5S
Molecular Weight	335.335
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)[N+]([O-])=O

InChI

InChIKey=GWBPFRGXNGPPMF-UHFFFAOYSA-N

InChI=1S/C14H13N3O5S/c1-10(18)15-11-4-8-14(9-5-11)23(21,22)16-12-2-6-13(7-3-12)17(19)20/h2-9,16H,1H3,(H,15,18)

HIDE SMILES / InChI

Molecular Formula	C14H13N3O5S
Molecular Weight	335.335
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugs.com/international/sulfanitran.html | https://www.gpo.gov/fdsys/pkg/CFR-1998-title21-vol6/pdf/CFR-1998-title21-vol6-sec520-2320.pdf

Sulfanitran is a sulfonamide antiinfective drug. It was approved for veterinary use as an aid in the treatment of coccidiosis caused by E. tenella, E. necatrix, and E. acervulina..

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Eimeria tenella 10 Target ID: CHEMBL612854 Sources: https://www.gpo.gov/fdsys/pkg/CFR-1998-title21-vol6/pdf/CFR-1998-title21-vol6-sec520-2320.pdf \| https://www.ncbi.nlm.nih.gov/pubmed/5459869	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Coccidiosis 45 Sources: https://www.gpo.gov/fdsys/pkg/CFR-1998-title21-vol6/pdf/CFR-1998-title21-vol6-sec520-2320.pdf https://www.drugs.com/international/sulfanitran.html https://www.ncbi.nlm.nih.gov/pubmed/5459869	Curative		Approved 8429	Novastat Approved Use Indications for use. As an aid in the treatment of coccidiosis caused by E. tenella, E. necatrix, and E. acervulina.

PubMed

Title	Date	PubMed
Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.	1996 Dec	9039272
Influence of luminal monosaccharides on secretion of glutathione conjugates from rat small intestine in vitro.	2009 Nov 3	19782883

Patents

Sample Use Guides

In Vivo Use Guide

Poultry: conditions of use. It is used in the drinking water of chickens as follows: Amount. 374–747 milligrams of sulfanitran with 477–954 milligrams of aklomide.

Route of Administration: Oral

In Vitro Use Guide

500 uM sulfanitran stimulated the vectorial transport of saquinavir, a recently described MRP2 substrate, across polarized MDCKII monolayers demonstrating that it also stimulates MRP2 in intact cells.

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:48:26 GMT 2023` Edited by `admin` on `Sat Dec 16 15:48:26 GMT 2023`
Record UNII	QT35T5T35Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFANITRAN

Official Name

English

UNISTAT 2 COMPONENT SULFANITRAN

Common Name

English

SULFANITRAN [MART.]

Common Name

English

SULFANITRAN [GREEN BOOK]

Common Name

English

sulfanitran [INN]

Common Name

English

NSC-77120

Code

English

ACETAMIDE, N-(4-(((4-NITROPHENYL)AMINO)SULFONYL)PHENYL)-

Systematic Name

English

SULFANITRAN [USAN]

Common Name

English

SULFANITRAN [MI]

Common Name

English

4'-((P-NITROPHENYL)SULFAMOYL)ACETANILIDE

Common Name

English

NSC-217299

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29739