DEBOXAMET

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H14N2O3
Molecular Weight	234.2512
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(NC(C)=C2CC(=O)NO)C=C1

InChI

InChIKey=VXMGLMHPFWGAJO-UHFFFAOYSA-N

InChI=1S/C12H14N2O3/c1-7-9(6-12(15)14-16)10-5-8(17-2)3-4-11(10)13-7/h3-5,13,16H,6H2,1-2H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C12H14N2O3
Molecular Weight	234.2512
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://patents.google.com/patent/US3624103 | http://www.ncbi.nlm.nih.gov/pubmed/3066776

Deboxamet is a synthetic drug with anti-ulcer and anti-secretory activity, discovered by the Italian Istituto Biologico Chemioterapico ABC, S.p.A. The compound is claimed to have high anti-inflammatory action, as evidenced by the results of the tests of acute and chronic experimental phlogosis. Deboxamet demonstrated cytoprotective activity in a model of rat gastric mucosa necrosis. The cytoprotective effect of deboxamet is mediated by the rise of the availability of prostacyclins in the rat gastric mucosa.

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:31:14 GMT 2025` Edited by `admin` on `Mon Mar 31 18:31:14 GMT 2025`
Record UNII	QJH0XA6AW9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DEBOXAMET

Official Name

English

deboxamet [INN]

Preferred Name

English

5-METHOXY-2-METHYLINDOLE-3-ACETOHYDROXAMIC ACID

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29701