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Details

Stereochemistry ACHIRAL
Molecular Formula C12H14N2O3
Molecular Weight 234.2512
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEBOXAMET

SMILES

COC1=CC2=C(NC(C)=C2CC(=O)NO)C=C1

InChI

InChIKey=VXMGLMHPFWGAJO-UHFFFAOYSA-N
InChI=1S/C12H14N2O3/c1-7-9(6-12(15)14-16)10-5-8(17-2)3-4-11(10)13-7/h3-5,13,16H,6H2,1-2H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula C12H14N2O3
Molecular Weight 234.2512
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Deboxamet is a synthetic drug with anti-ulcer and anti-secretory activity, discovered by the Italian Istituto Biologico Chemioterapico ABC, S.p.A. The compound is claimed to have high anti-inflammatory action, as evidenced by the results of the tests of acute and chronic experimental phlogosis. Deboxamet demonstrated cytoprotective activity in a model of rat gastric mucosa necrosis. The cytoprotective effect of deboxamet is mediated by the rise of the availability of prostacyclins in the rat gastric mucosa.

Approval Year

Substance Class Chemical
Record UNII
QJH0XA6AW9
Record Status Validated (UNII)
Record Version