JNJ-26990990

NS(=O)(=O)NCC1=CSC2=CC=CC=C12

InChIKey=AWSKBQNOSRREEY-UHFFFAOYSA-N

InChI=1S/C9H10N2O2S2/c10-15(12,13)11-5-7-6-14-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H2,10,12,13)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Sodium channel protein type II alpha subunit 27 Target ID: CHEMBL4187 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19388676	Inhibitor 8504		48.0 µM [IC50]
Voltage-dependent N-type calcium channel subunit alpha-1B 2 Target ID: Q00975 Gene ID: 774.0 Gene Symbol: CACNA1B Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/19388676	Inhibitor 8504		28.0 µM [IC50]

PubMed

Title	Date	PubMed
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.	2009-12-10	19388676

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:31:45 GMT 2025` Edited by `admin` on `Mon Mar 31 22:31:45 GMT 2025`
Record UNII	QFG58Y96EP
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

N-((BENZO(B)THIEN-3-YL)METHYL)SULFAMIDE

Preferred Name

English

JNJ-26990990

Common Name

English

SULFAMIDE, (BENZO(B)THIEN-3-YLMETHYL)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

11687376