SSR-180711

BrC1=CC=C(OC(=O)N2CCN3CCC2CC3)C=C1

InChIKey=RXLOZRCLQMJJLC-UHFFFAOYSA-N

InChI=1S/C14H17BrN2O2/c15-11-1-3-13(4-2-11)19-14(18)17-10-9-16-7-5-12(17)6-8-16/h1-4,12H,5-10H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Neuronal acetylcholine receptor subunit alpha-7 14 Target ID: P36544 Gene ID: 1139\|\|\|89832 Gene Symbol: CHRNA7 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/17019409	Partial Agonist 297		14.0 nM [Ki]
Neuronal acetylcholine receptor subunit alpha-7 14 Target ID: P36544 Gene ID: 1139\|\|\|89832 Gene Symbol: CHRNA7 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/16936709 \| https://www.ncbi.nlm.nih.gov/pubmed/17019409	Partial Agonist 297		14.0 nM [Ki]

PubMed

Title	Date	PubMed
α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease.	2010-05-27	21249164
Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice.	2009-01-05	18848931

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:46:47 GMT 2025` Edited by `admin` on `Mon Mar 31 21:46:47 GMT 2025`
Record UNII	QF4P1U1666
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

J2.849.107G

Preferred Name

English

SSR-180711

Code

English

SSR-180,711

Code

English

4-BROMOPHENYL 1,4-DIAZABICYCLO(3.2.2)NONANE-4-CARBOXYLATE

Systematic Name

English

1,4-DIAZABICYCLO(3.2.2)NONANE-4-CARBOXYLIC ACID, 4-BROMOPHENYL ESTER

Systematic Name

English

Code System Code Type Description

PUBCHEM

9797360