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Details

Stereochemistry ABSOLUTE
Molecular Formula C60H108O8
Molecular Weight 957.4947
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 3
Charge 0

SHOW SMILES / InChI
Structure of SORBITAN TRIOLEATE

SMILES

[H][C@@]1(OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@@H](COC(=O)CCCCCCC\C=C/CCCCCCCC)OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

InChIKey=PRXRUNOAOLTIEF-ADSICKODSA-N
InChI=1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-/t54-,55+,59+,60+/m0/s1

HIDE SMILES / InChI
Molecular Formula C60H108O8
Molecular Weight 957.4947
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 3
Optical Activity UNSPECIFIED

Description

Sorbitan Trioleate (Tween 85) is a triester of oleic acid and hexitol anhydrides derived from sorbitol. It functions as a surfactant and emulsifying agent. This product is a white to tan-colored solid. In cosmetics and personal care products, Sorbitan Esters are used in a variety of products including skin care products, skin cleansing products, moisturizers, eye makeup and other makeup.

Approval Year

1990
108
PubMed

PubMed

TitleDatePubMed
Crystallization kinetics of cocoa butter in the presence of sorbitan esters.
2017 Jan 1

Sample Use Guides

In Vivo Use Guide
Subacute toxicity of sorbitan trioleate (STO) was carried out using Wistar rats. STO was administered intravenously at dose levels of 12.5, 50.0 and 200.0 mg/kg for 35 days. No influence on general symptom, body weight, food and water consumption and urinalysis were observed. In 200.0 mg/kg group, the hematological examination revealed anemia corresponding to the histological findings of the bone marrow. Biochemical analysis displayed the significant increase and/or decrease of enzyme values in 200.0 mg/kg group. The maximal no-effect level of the STO in Wistar rats was considered to be 50.0 mg/kg.
Route of Administration: Intravenous
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:00:02 GMT 2023
Edited
by admin
on Fri Dec 15 15:00:02 GMT 2023
Record UNII
QE6F49RPJ1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SORBITAN TRIOLEATE
EP   II   INCI   INN   MART.   USAN   VANDF  
INCI   USAN   INN  
Official Name English
ARLACEL 85
Brand Name English
SORBITAN TRIOLEATE [INCI]
Common Name English
SPAN85
Common Name English
SORBITAN, TRI-9-OCTADECENOATE
Common Name English
SORBITAN TRIOLEATE [II]
Common Name English
SORBITAN TRIOLEATE [MART.]
Common Name English
SPAN-85
Common Name English
MF59 COMPONENT SPAN85
Common Name English
SORBITAN TRIOLEATE [USAN]
Common Name English
SORBITAN TRIOLEATE [EP MONOGRAPH]
Common Name English
SPAN 85
Brand Name English
ANHYDROSORBITOL TRIOLEATE
Common Name English
sorbitan trioleate [INN]
Common Name English
SORBITAN TRIOLEATE [VANDF]
Common Name English
SORBITAN, TRI-(9Z)-9-OCTADECENOATE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C83486
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
Code System Code Type Description
FDA UNII
QE6F49RPJ1
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
EPA CompTox
DTXSID6027892
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
NCI_THESAURUS
C75657
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
INN
1876
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
CAS
70024-41-8
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
ALTERNATIVE
PUBCHEM
9920343
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
CAS
26266-58-0
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
EVMPD
SUB10602MIG
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
SMS_ID
100000083814
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
ECHA (EC/EINECS)
247-569-3
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
CAS
2599-45-3
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
ALTERNATIVE
RXCUI
1363643
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY RxNorm
MESH
C005693
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
DAILYMED
QE6F49RPJ1
Created by admin on Fri Dec 15 15:00:02 GMT 2023 , Edited by admin on Fri Dec 15 15:00:02 GMT 2023
PRIMARY
Related Record Type Details
Structure of SORBITAN TRIOLEATE
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