U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry MIXED
Molecular Formula C15H12N2O2
Molecular Weight 252.268
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CARBAMAZEPINE-10,11-EPOXIDE

SMILES

NC(=O)N1C2=CC=CC=C2C3OC3C4=CC=CC=C14

InChI

InChIKey=ZRWWEEVEIOGMMT-UHFFFAOYSA-N
InChI=1S/C15H12N2O2/c16-15(18)17-11-7-3-1-5-9(11)13-14(19-13)10-6-2-4-8-12(10)17/h1-8,13-14H,(H2,16,18)

HIDE SMILES / InChI

Molecular Formula C15H12N2O2
Molecular Weight 252.268
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Transitional polytherapy: tricks of the trade for monotherapy to monotherapy AED conversions.
2009-06
Approaches to treatment of type 2 diabetes.
2008-08
Transcriptional profiling of genes induced in the livers of patients treated with carbamazepine.
2006-11
Patterns of care, outcomes, and direct health plan costs of antiepileptic therapy: a pharmacoeconomic analysis of the available carbamazepine formulations.
2005-07
Effect of probenecid on the pharmacokinetics of carbamazepine in healthy subjects.
2005-06
Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.
2005-03
In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine.
2003-06
Elevation of carbamazepine-10,11-epoxide by quetiapine.
2002-11
Reanalysis of carbamazepine and carbamazepine-epoxide pharmacokinetics after multiple dosing of extended release formulation.
2002-09-05
Administration of Carbatrol to children with feeding tubes.
2002-09
The influence of food on the bioavailability of a twice-daily controlled release carbamazepine formulation.
2001-02
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:56:20 GMT 2025
Edited
by admin
on Mon Mar 31 21:56:20 GMT 2025
Record UNII
QC9505F279
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CARBAMAZEPINE-10,11-EPOXIDE
Common Name English
GP-49-023
Preferred Name English
CBZ-E
Common Name English
6H-DIBENZ(B,F)OXIRENO(D)AZEPINE-6-CARBOXAMIDE, 1A,10B-DIHYDRO-
Common Name English
10,11-DIHYDRO-10,11-EPOXYCARBAMAZEPINE
Common Name English
CARBAMAZEPINE EPOXIDE
Common Name English
10,11-EPOXYCARBAMAZEPINE
Common Name English
CARBAMAZEPINE 10,11-OXIDE
Common Name English
10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE 10,11-EPOXIDE
Common Name English
Code System Code Type Description
CAS
36507-30-9
Created by admin on Mon Mar 31 21:56:20 GMT 2025 , Edited by admin on Mon Mar 31 21:56:20 GMT 2025
PRIMARY
EPA CompTox
DTXSID60891456
Created by admin on Mon Mar 31 21:56:20 GMT 2025 , Edited by admin on Mon Mar 31 21:56:20 GMT 2025
PRIMARY
CHEBI
3388
Created by admin on Mon Mar 31 21:56:20 GMT 2025 , Edited by admin on Mon Mar 31 21:56:20 GMT 2025
PRIMARY
FDA UNII
QC9505F279
Created by admin on Mon Mar 31 21:56:20 GMT 2025 , Edited by admin on Mon Mar 31 21:56:20 GMT 2025
PRIMARY
PUBCHEM
2555
Created by admin on Mon Mar 31 21:56:20 GMT 2025 , Edited by admin on Mon Mar 31 21:56:20 GMT 2025
PRIMARY
Related Record Type Details
BINDER->LIGAND
Related Record Type Details
PRODRUG -> METABOLITE ACTIVE