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Details

Stereochemistry MIXED
Molecular Formula C15H12N2O2
Molecular Weight 252.2685
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CARBAMAZEPINE-10,11-EPOXIDE

SMILES

c1ccc2c(c1)C3C(c4ccccc4N2C(=N)O)O3

InChI

InChIKey=ZRWWEEVEIOGMMT-UHFFFAOYSA-N
InChI=1S/C15H12N2O2/c16-15(18)17-11-7-3-1-5-9(11)13-14(19-13)10-6-2-4-8-12(10)17/h1-8,13-14H,(H2,16,18)

HIDE SMILES / InChI

Molecular Formula C15H12N2O2
Molecular Weight 252.2685
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
The influence of food on the bioavailability of a twice-daily controlled release carbamazepine formulation.
2001 Feb
Reanalysis of carbamazepine and carbamazepine-epoxide pharmacokinetics after multiple dosing of extended release formulation.
2002 May-Aug
Elevation of carbamazepine-10,11-epoxide by quetiapine.
2002 Nov
Administration of Carbatrol to children with feeding tubes.
2002 Sep
Patterns of care, outcomes, and direct health plan costs of antiepileptic therapy: a pharmacoeconomic analysis of the available carbamazepine formulations.
2005 Jul
Effect of probenecid on the pharmacokinetics of carbamazepine in healthy subjects.
2005 Jun
Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.
2005 Mar
Transcriptional profiling of genes induced in the livers of patients treated with carbamazepine.
2006 Nov
Approaches to treatment of type 2 diabetes.
2008 Aug
Transitional polytherapy: tricks of the trade for monotherapy to monotherapy AED conversions.
2009 Jun
Substance Class Chemical
Created
by admin
on Fri Jun 25 22:34:03 UTC 2021
Edited
by admin
on Fri Jun 25 22:34:03 UTC 2021
Record UNII
QC9505F279
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CARBAMAZEPINE-10,11-EPOXIDE
Common Name English
CBZ-E
Common Name English
6H-DIBENZ(B,F)OXIRENO(D)AZEPINE-6-CARBOXAMIDE, 1A,10B-DIHYDRO-
Common Name English
10,11-DIHYDRO-10,11-EPOXYCARBAMAZEPINE
Common Name English
CARBAMAZEPINE EPOXIDE
Common Name English
10,11-EPOXYCARBAMAZEPINE
Common Name English
CARBAMAZEPINE 10,11-OXIDE
Common Name English
GP-49-023
Code English
10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE 10,11-EPOXIDE
Common Name English
Code System Code Type Description
CAS
36507-30-9
Created by admin on Fri Jun 25 22:34:03 UTC 2021 , Edited by admin on Fri Jun 25 22:34:03 UTC 2021
PRIMARY
FDA UNII
QC9505F279
Created by admin on Fri Jun 25 22:34:03 UTC 2021 , Edited by admin on Fri Jun 25 22:34:03 UTC 2021
PRIMARY
PUBCHEM
2555
Created by admin on Fri Jun 25 22:34:03 UTC 2021 , Edited by admin on Fri Jun 25 22:34:03 UTC 2021
PRIMARY
Related Record Type Details
BINDER->LIGAND
Related Record Type Details
PARENT -> METABOLITE ACTIVE