SRA-737

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H16F3N7O
Molecular Weight	379.3397
Optical Activity	( + )
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC(F)(F)C1=CN=C(NC2=CN=C(C=N2)C#N)C=C1NC[C@H]3CNCCO3

InChI

InChIKey=YBYYWUUUGCNAHQ-LLVKDONJSA-N

InChI=1S/C16H16F3N7O/c17-16(18,19)12-8-25-14(26-15-9-22-10(4-20)5-24-15)3-13(12)23-7-11-6-21-1-2-27-11/h3,5,8-9,11,21H,1-2,6-7H2,(H2,23,24,25,26)/t11-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C16H16F3N7O
Molecular Weight	379.3397
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Serine/threonine-protein kinase Chk1 20 Target ID: CHEMBL4630 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27167172	Inhibitor 8297		1.3 nM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:43:44 UTC 2023` Edited by `admin` on `Sat Dec 16 18:43:44 UTC 2023`
Record UNII	QB6LNL4NF6
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SRA-737

Code

English

CCT-245737

Code

English

PNT-737

Code

English

SRA-737 [WHO-SDG]

Common Name

English

(R)-5-((4-((MORPHOLIN-2-YLMETHYL)AMINO)-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL)AMINO)PYRAZINE-2-CARBONITRILE

Systematic Name

English

2-PYRAZINECARBONITRILE, 5-((4-(((2R)-2-MORPHOLINYLMETHYL)AMINO)-5-(TRIFLUOROMETHYL)-2-PYRIDINYL)AMINO)-

Systematic Name

English

SRA 737 [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

72165232