Cenzileucel

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 19:32:12 GMT 2023` Edited by `admin` on `Sat Dec 16 19:32:12 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	AUTOLOGOUS HUMAN
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part Location	TUMOR
Part	SKIN
Fraction Name	autologous tumor-infiltrating lymphocytes (TILs)
Record UNII	Q5KB23UV6Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Cenzileucel

Official Name

English

cenzileucel [INN]

Common Name

English

human culture-expanded activated autologous T lymphocytes for cell-based immunotherapy. The cells are mechanically and enzymatically isolated from resected tumour biopsy of patients with metastatic melanoma and cultured in media containing recombinant in

Common Name

English

Code System Code Type Description

FDA UNII

Q5KB23UV6Q

Created by admin on Sat Dec 16 19:32:12 GMT 2023 , Edited by admin on Sat Dec 16 19:32:12 GMT 2023

PRIMARY

INN

12313

Created by admin on Sat Dec 16 19:32:12 GMT 2023 , Edited by admin on Sat Dec 16 19:32:12 GMT 2023

PRIMARY

Related Record Type Details


					Q5KB23UV6Q

Cenzileucel

ACTIVE MOIETY

Comments:

T lymphocytes demonstrate the ability to kill and impede tumour growth in a co-culture based cytotoxicity assay

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Fragment Name	Fragment ID
CULTURED	EXPANSION	BIOLOGICAL	ALDESLEUKIN	M89N0Q7EQR
CULTURE	EXPANSION	BIOLOGICAL	FETAL SERUM, BOVINE	K5DD3J879P
CULTURE	ACTIVATOR	BIOLOGICAL	ALBUMIN HUMAN	ZIF514RVZR
CULTURE	ACTIVATOR	BIOLOGICAL	Irradiated PBMC	4Z7WSE8RR2
CULTURE		BIOLOGICAL	HUMAN INTERLEUKIN-2	FNO32LO217
CULTURE	ACTIVATOR	BIOLOGICAL	MUROMONAB-CD3	JGA39ICE2V