SALMEFAMOL

Details

Stereochemistry	UNKNOWN
Molecular Formula	C19H25NO4
Molecular Weight	331.4061
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(CC(C)NCC(O)C2=CC(CO)=C(O)C=C2)C=C1

InChI

InChIKey=VPMWDFRZSIMDKW-UHFFFAOYSA-N

InChI=1S/C19H25NO4/c1-13(9-14-3-6-17(24-2)7-4-14)20-11-19(23)15-5-8-18(22)16(10-15)12-21/h3-8,10,13,19-23H,9,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H25NO4
Molecular Weight	331.4061
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1173987 | https://www.ncbi.nlm.nih.gov/pubmed/580407

Salmefamol is a beta2-adrenoceptor agonist that was studied in asthmatic patients. In clinical trials, the drug had shown marked efficacy with low toxicity and was generally well tolerated. However, information about the further development of salmefamol as a bronchodilator drug is not available.

Approval Year

PubMed

Title	Date	PubMed
The bronchodilator effect of a new adrenergic aerosol--Salmefamol.	1972 Feb	5067420
The clinical pharmacology of salmefamol.	1974 Oct	22454916

Sample Use Guides

In Vivo Use Guide

Twenty-five asthmatics were tested with salmefamol aerosol (200 mug q.d.s.) for a period of 3 months.

Route of Administration: Respiratory

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:24:59 GMT 2023` Edited by `admin` on `Sat Dec 16 17:24:59 GMT 2023`
Record UNII	Q56SEY8X9J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SALMEFAMOL

Official Name

English

AH-3923

Code

English

salmefamol [INN]

Common Name

English

AH 3923

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C48149