EDETOL

Details

Stereochemistry	MIXED
Molecular Formula	C14H32N2O4
Molecular Weight	292.4149
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O

InChI

InChIKey=NSOXQYCFHDMMGV-UHFFFAOYSA-N

InChI=1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C14H32N2O4
Molecular Weight	292.4149
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3246540 | https://www.ncbi.nlm.nih.gov/pubmed/3235611 | http://www.matweb.com/search/datasheettext.aspx?matguid=e6253ff195784ec0a57af61cedf5ba85

Quadrol, N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine, also known as edetol, is a registered trademark of BASF Corporation. Quadrol has proven to be an excellent cross-linking agent and catalyst for use in polyurethane coatings and rigid foams. The four hydroxyl groups in quadrol give multiple cross-linking sites and the two tertiary nitrogen atoms provide catalysis for the reaction. In addition, was studied the biological activity of quadrol: this compound promoted in vivo collagen synthesis and was effective as a stimulator of wound healing in diabetic and non-diabetic animals. Quadrol exists as a mixture of four unique diastereomers, each of which may display differences in biological activity.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Metal complexes of tetrapodal ligands: synthesis, spectroscopic and thermal studies, and X-ray crystal structure studies of Na(I), Ca(II), Sr(II), and Ba(II) complexes of tetrapodal ligands N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine and N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine.	2002 Apr 22	11952361
The behavior of organic components in copper recovery from electroless plating bath effluents using 3D electrode systems.	2004 Aug 30	15302447
Magnetic resonance flow velocity and temperature mapping of a shape memory polymer foam device.	2009 Dec 31	20043833
Sorption of Cu(II) complexes with ligands tartrate, glycine and quadrol by chitosan.	2009 Nov 15	19540041
Decontamination of solutions containing Cu(II) and ligands tartrate, glycine and quadrol using metallic iron.	2010 Mar 15	19896768

Patents

Sample Use Guides

In Vivo Use Guide

normal and diabetic mice: the rate of collagen deposition in implanted polytetrafluoroethylene (PTFE) tubing in non-diabetic and streptozotocin-induced (STZ) diabetic mice was measured during 14 days post-wounding. At the time of implantation, test groups received injections of either quadrol (edetol; N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine], glucan, or buffer in an area adjacent to the wound site. Quadrol promotes in vivo collagen synthesis and that quadrol may be effective as a stimulator of wound healing in diabetic and non-diabetic animals.

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:41:18 UTC 2023` Edited by `admin` on `Fri Dec 15 17:41:18 UTC 2023`
Record UNII	Q4R969U9FR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EDETOL

Official Name

English

2-PROPANOL, 1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS-

Systematic Name

English

edetol [INN]

Common Name

English

N,N,N',N'-TETRAKIS (2-HYDROXYPROPYL) ETHYLENEDIAMINE

Systematic Name

English

QUADROL

Brand Name

English

EDETOL [HSDB]

Common Name

English

NEUTROL TE

Brand Name

English

TETRAHYDROXYPROPYL ETHYLENEDIAMINE

Official Name

English

NSC-369219

Code

English

1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS(2-PROPANOL)

Systematic Name

English

N,N,N',N'-TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE

Systematic Name

English

TETRAHYDROXYPROPYL ETHYLENEDIAMINE [INCI]

Common Name

English

ENTPROL [MI]

Common Name

English

EDETOL [USAN]

Common Name

English

Code System Code Type Description

INN

5313