CLORANOLOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H19Cl2NO2
Molecular Weight	292.201
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)NCC(O)COC1=C(Cl)C=CC(Cl)=C1

InChI

InChIKey=XYCMOTOFHFTUIU-UHFFFAOYSA-N

InChI=1S/C13H19Cl2NO2/c1-13(2,3)16-7-10(17)8-18-12-6-9(14)4-5-11(12)15/h4-6,10,16-17H,7-8H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C13H19Cl2NO2
Molecular Weight	292.201
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2868999 | https://www.ncbi.nlm.nih.gov/pubmed/1685755 | Tardos, L., Szekeres, L., Papp, Gy,J. (2013) Pharmacological Control of Heart and Circulation, page 253, retrieved from: https://books.google.ru/books?id=w14hBQAAQBAJ | https://www.drugfuture.com/chemdata/Cloranolol.html

Cloranolol is a specific beta-adrenergic antagonist. It is used as an antiarrhythmic agent. Its antiarrhythmic effectiveness stronger than propranol and equal or surpass the effectivity of pindolol. It has a negligible cardiodepressant activity as compared to other beta-adrenergic antagonists. Cloranolol has mainly cardiorespiratory side effects judging from the beta-blocker characteristics

Approval Year

PubMed

Title	Date	PubMed
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.	2010-12	21818443
Pharmacology of GYKI-41 099 (chlorpropanol, Tobanum) a new potent beta-adrenergic antagonist.	1980-12	6111982

Sample Use Guides

In Vivo Use Guide

Single dose - 10 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:57:08 GMT 2025` Edited by `admin` on `Wed Apr 02 09:57:08 GMT 2025`
Record UNII	Q3U058H86V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLORANOLOL

Official Name

English

CLORANOLOL [MI]

Preferred Name

English

1-(TERT-BUTYLAMINO)-3-(2,5-DICHLOROPHENOXY)-2-PROPANOL

Systematic Name

English

cloranolol [INN]

Common Name

English

TOBANUM

Brand Name

English

CHLORANOLOL

Common Name

English

Cloranolol [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-ATC

C07AA27