Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C24H27NO7 |
Molecular Weight | 441.4737 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 6 / 6 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12[C@@H]3C[C@@H]4C[C@]1(C[C@]4(C)O3)C=CC(=O)[C@@]2(C)CCC(=O)NC5=C(O)C(=CC=C5O)C(O)=O
InChI
InChIKey=CSOMAHTTWTVBFL-OFBLZTNGSA-N
InChI=1S/C24H27NO7/c1-22(7-6-17(28)25-18-14(26)4-3-13(19(18)29)21(30)31)16(27)5-8-24-10-12-9-15(20(22)24)32-23(12,2)11-24/h3-5,8,12,15,20,26,29H,6-7,9-11H2,1-2H3,(H,25,28)(H,30,31)/t12-,15+,20+,22-,23+,24+/m1/s1
Molecular Formula | C24H27NO7 |
Molecular Weight | 441.4737 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 6 / 6 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
[An old pathway to new antibiotics--platensimycin]. | 2006 |
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Total synthesis of platensimycin. | 2006 Oct 27 |
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Structure-assisted discovery of an aminothiazole derivative as a lead molecule for inhibition of bacterial fatty-acid synthesis. | 2007 Dec |
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Biosynthetic studies of platensimycin. | 2007 Dec 19 |
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Mining and engineering natural-product biosynthetic pathways. | 2007 Jul |
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An expedient enantioselective strategy for the oxatetracyclic core of platensimycin. | 2007 Jun 7 |
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Antibacterial targets in fatty acid biosynthesis. | 2007 Oct |
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Enantioselective synthesis of (-)-platensimycin oxatetracyclic core by using an intramolecular Diels-Alder reaction. | 2007 Sep 27 |
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High-pressure entry into platencin. | 2008 |
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Synthesis of platensimycin. | 2008 |
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Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity. | 2008 Oct 1 |
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Stereocontrolled formal synthesis of (+/-)-platensimycin. | 2008 Sep 18 |
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Isoplatensimycin: Synthesis and biological evaluation. | 2009 Aug 15 |
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Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. | 2009 Jul 17 |
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Stereoelectronic effect for the selectivity in C-H insertion of alkylidene carbenes and its application to the synthesis of platensimycin. | 2009 Jun 24 |
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Synthesis and biological evaluation of platensimycin analogs. | 2009 Mar 15 |
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Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure. | 2009 Nov |
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Total syntheses of (+/-)-platencin and (-)-platencin. | 2009 Nov 4 |
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Isolation, structure and biological activities of platencin A(2)-A(4) from Streptomyces platensis. | 2010 Apr 1 |
|
Coping with antibiotic resistance: contributions from genomics. | 2010 Feb 25 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:34:11 GMT 2023
by
admin
on
Sat Dec 16 09:34:11 GMT 2023
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Record UNII |
Q3DQ78KOFY
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Record Status |
Validated (UNII)
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Record Version |
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6857724
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835876-32-9
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m8910
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Platensimycin
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DTXSID80894888
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Q3DQ78KOFY
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DB08407
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