ESCALINE

CCOC1=C(OC)C=C(CCN)C=C1OC

InChIKey=RHOGRSKNWDNCDN-UHFFFAOYSA-N

InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2a (5-HT2a) receptor 231 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18666267 \| https://www.ncbi.nlm.nih.gov/pubmed/9301661	Agonist 2678		216.0 nM [Ki]
Serotonin 2c (5-HT2c) receptor 124 Target ID: CHEMBL324 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9301661	Agonist 2678		2.0 µM [EC50]

PubMed

Title	Date	PubMed
Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives.	1997 Sep 12	9301661
Structure-activity relationships of phenylalkylamines as agonist ligands for 5-HT(2A) receptors.	2008 Sep	18666267

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:01:35 GMT 2023` Edited by `admin` on `Sat Dec 16 11:01:35 GMT 2023`
Record UNII	Q13F1C1N8I
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ESCALINE

Common Name

English

BENZENEETHANAMINE, 4-ETHOXY-3,5-DIMETHOXY-

Systematic Name

English

2-(4-ETHOXY-3,5-DIMETHOXYPHENYL)ETHANAMINE

Systematic Name

English

3,5-Dimethoxy-4-ethoxyphenethylamine

Common Name

English

ETHYLAMINE, 3,5-DIMETHOXY-4-ETHOXYPHENYL-

Systematic Name

English

E (PSYCHEDELIC)

Common Name

English

Classification Tree Code System Code

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