DIBUTYL SUCCINATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H22O4
Molecular Weight	230.3007
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCOC(=O)CCC(=O)OCCCC

InChI

InChIKey=YUXIBTJKHLUKBD-UHFFFAOYSA-N

InChI=1S/C12H22O4/c1-3-5-9-15-11(13)7-8-12(14)16-10-6-4-2/h3-10H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C12H22O4
Molecular Weight	230.3007
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC33464 | https://www.google.com/patents/US4902504 | https://www.ncbi.nlm.nih.gov/pubmed/8938020 | https://www.google.com/patents/US4911906

Dibutyl succinate is used as an insecticide, surfactant and insect attractant. Preliminary investigations have found that dibutyl succinate exhibits insulinotropic action on isolated islet cells suggesting that it may have some application for the treatment of diabetes.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Diabetes mellitus 91 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8938020	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Biodegradation of poly(tetramethylene succinate-co-tetramethylene adipate) and poly(tetramethylene succinate) through water-soluble products.	2001 May	11337881
Cloning and sequence analysis of poly(tetramethylene succinate) depolymerase from Acidovorax delafieldii strain BS-3.	2002	16233195
Molecular structure of crude beeswax studied by solid-state 13C NMR.	2004	15861244
Biodegradability of plastics.	2009 Aug 26	19865515

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Groups of eight islets were each incubated for 90 min in 1.0 mL of a bicarbonate-buffered medium containing bovine serum albumin (5.0 mg/mL) and D-glucose (7.0 mM) and 10 mM of dibutyl succinate. The insulin released by the islets in the incubation medium was then assayed by a radioimmunological back titration. dibutyl succinate significantly augmented insulin release by +24.8 micor-U per in the 90 min incubation period.

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:47:45 GMT 2023` Edited by `admin` on `Fri Dec 15 17:47:45 GMT 2023`
Record UNII	Q050512U41
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIBUTYL SUCCINATE

Systematic Name

English

NSC-1502

Code

English

DIBUTYLSUCCINATE

Systematic Name

English

DIBUTYL SUCCINATE [MI]

Common Name

English

DIBUTYL SUCCINATE [HSDB]

Common Name

English

DIBUTYL BUTANEDIOATE

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QP53GX03