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Details

Stereochemistry ACHIRAL
Molecular Formula C12H22O4
Molecular Weight 230.3007
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIBUTYL SUCCINATE

SMILES

CCCCOC(=O)CCC(=O)OCCCC

InChI

InChIKey=YUXIBTJKHLUKBD-UHFFFAOYSA-N
InChI=1S/C12H22O4/c1-3-5-9-15-11(13)7-8-12(14)16-10-6-4-2/h3-10H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C12H22O4
Molecular Weight 230.3007
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Dibutyl succinate is used as an insecticide, surfactant and insect attractant. Preliminary investigations have found that dibutyl succinate exhibits insulinotropic action on isolated islet cells suggesting that it may have some application for the treatment of diabetes.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Groups of eight islets were each incubated for 90 min in 1.0 mL of a bicarbonate-buffered medium containing bovine serum albumin (5.0 mg/mL) and D-glucose (7.0 mM) and 10 mM of dibutyl succinate. The insulin released by the islets in the incubation medium was then assayed by a radioimmunological back titration. dibutyl succinate significantly augmented insulin release by +24.8 micor-U per in the 90 min incubation period.
Substance Class Chemical
Record UNII
Q050512U41
Record Status Validated (UNII)
Record Version