Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H10O5 |
| Molecular Weight | 246.2155 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC(O)=C(C=C1)C(=O)C2=C(O)C=C(O)C=C2
InChI
InChIKey=WXNRYSGJLQFHBR-UHFFFAOYSA-N
InChI=1S/C13H10O5/c14-7-1-3-9(11(16)5-7)13(18)10-4-2-8(15)6-12(10)17/h1-6,14-17H
| Molecular Formula | C13H10O5 |
| Molecular Weight | 246.2155 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Estrogenic activity of phenolic additives determined by an in vitro yeast bioassay. | 2001 Feb |
|
| Comparison of the reporter gene assay for ER-alpha antagonists with the immature rat uterotrophic assay of 10 chemicals. | 2003 Apr 30 |
|
| Immature rat uterotrophic assay of 18 chemicals and Hershberger assay of 30 chemicals. | 2003 Feb 1 |
|
| Effects of estradiol, benzophenone-2 and benzophenone-3 on the expression pattern of the estrogen receptors (ER) alpha and beta, the estrogen receptor-related receptor 1 (ERR1) and the aryl hydrocarbon receptor (AhR) in adult ovariectomized rats. | 2004 Dec 1 |
|
| Pure estrogenic effect of benzophenone-2 (BP2) but not of bisphenol A (BPA) and dibutylphtalate (DBP) in uterus, vagina and bone. | 2004 Dec 1 |
|
| Multi-organic endocrine disrupting activity of the UV screen benzophenone 2 (BP2) in ovariectomized adult rats after 5 days treatment. | 2004 Dec 1 |
|
| [Estrogenic activity of ultraviolet absorbers and the related compounds]. | 2005 Aug |
|
| Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens. | 2005 Feb 15 |
|
| Effects of bisphenol-A (BPA), dibutylphtalate (DBP), benzophenone-2 (BP2), procymidone (Proc), and linurone (Lin) on fat tissue, a variety of hormones and metabolic parameters: a 3 months comparison with effects of estradiol (E2) in ovariectomized (ovx) rats. | 2005 Sep 15 |
|
| In vitro effects of benzophenone-2 and octyl-methoxycinnamate on the production of interferon-gamma and interleukin-10 by murine splenocytes. | 2006 |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
| A dose-response study on the estrogenic activity of benzophenone-2 on various endpoints in the serum, pituitary and uterus of female rats. | 2006 Oct |
|
| Effects of the UV filter benzophenone-2 on reproduction in fish. | 2007 Dec 15 |
|
| The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase. | 2007 Jun |
|
| In utero exposure to benzophenone-2 causes hypospadias through an estrogen receptor dependent mechanism. | 2007 Oct |
|
| Simultaneous trace determination of nine organic UV-absorbing compounds (UV filters) in environmental samples. | 2008 Aug 15 |
|
| Cloud point extraction combined with micellar electrokinetic capillary chromatography determination of benzophenones in cosmetic matrix. | 2008 Feb |
|
| Pharmacokinetics and metabolism of benzophenone 2 in the rat. | 2008 Mar 12 |
|
| Estrogenic activity of ternary UV filter mixtures in fish (Pimephales promelas) - an analysis with nonlinear isobolograms. | 2009 Jan 1 |
|
| Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications. | 2010 Feb 15 |
|
| True photoallergy to sunscreens is rare despite popular belief. | 2010 Jul-Aug |
|
| Effect of 2,2',4,4'-tetrahydroxybenzophenone (BP2) on steroidogenesis in testicular Leydig cells. | 2011 Oct 9 |
|
| Zebrafish eleutheroembryos provide a suitable vertebrate model for screening chemicals that impair thyroid hormone synthesis. | 2011 Sep 1 |
|
| Identification of classifiers for increase or decrease of thyroid peroxidase activity in the FTC-238/hTPO recombinant cell line. | 2011 Sep 15 |
|
| Selective activation of zebrafish estrogen receptor subtypes by chemicals by using stable reporter gene assay developed in a zebrafish liver cell line. | 2012 Feb |
|
| Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors. | 2014 Oct 1 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:51:17 GMT 2023
by
admin
on
Fri Dec 15 15:51:17 GMT 2023
|
| Record UNII |
PRR8K3H9VN
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
1315125
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | RxNorm | ||
|
8571
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | |||
|
205-028-9
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | |||
|
C035476
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | |||
|
131-55-5
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | |||
|
PRR8K3H9VN
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | |||
|
DTXSID5041306
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | |||
|
PRR8K3H9VN
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY | |||
|
38556
Created by
admin on Fri Dec 15 15:51:17 GMT 2023 , Edited by admin on Fri Dec 15 15:51:17 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
