N-ACETYLHISTIDINE MONOHYDRATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C8H11N3O3.H2O
Molecular Weight	215.2065
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of N-ACETYLHISTIDINE MONOHYDRATE

Structure Search

SMILES

O.CC(=O)N[C@@H](CC1=CNC=N1)C(O)=O

InChI

InChIKey=PSWSDQRXCOJSFC-FJXQXJEOSA-N

InChI=1S/C8H11N3O3.H2O/c1-5(12)11-7(8(13)14)2-6-3-9-4-10-6;/h3-4,7H,2H2,1H3,(H,9,10)(H,11,12)(H,13,14);1H2/t7-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C8H11N3O3
Molecular Weight	197.1912
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed

Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial cells.	2001 Dec	11859931
Characterization of sterically stabilized cisplatin liposomes by nuclear magnetic resonance.	2001 Feb 9	11342165
Interaction of copper(II) with imidazole pyridine nitrogen-containing ligands in aqueous medium: a spectroscopic study.	2002 Jan 1	11750023
Mechanisms of reactions of flavin mononucleotide triplet with aromatic amino acids.	2002 Jul	12164501
Model studies on protein side chain modification by 4-oxo-2-nonenal.	2003 Apr	12703968
Structural basis of protein-bound endogenous aldehydes. Chemical and immunochemical characterizations of configurational isomers of a 4-hydroxy-2-nonenal-histidine adduct.	2003 Feb 14	12473681
Ultraviolet spectrophotometric characterization of copper(II) complexes with imidazole N-methyl derivatives of L-histidine in aqueous solution.	2003 Jan 1	12509160
Purification and sequence identification of anserinase.	2005 Dec	16302965
Histidine nutrition and genotype affect cataract development in Atlantic salmon, Salmo salar L.	2005 Jun	15960659
3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.	2005 Jun 10	15817458
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation.	2005 May 17	15882077
Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.	2005 Oct	16244442
N-acetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release.	2006 Sep 28	16935380
Histidine-induced injury to cultured liver cells, effects of histidine derivatives and of iron chelators.	2007 Jan	17180300
Possible bioactivation pathways of lamotrigine.	2007 Jul	17409271
Detection of kynurenine modifications in proteins using a monoclonal antibody.	2007 Jul 31	17574268
Magnetic assembly and patterning of vesicle/nanoparticle aggregates.	2007 Oct 10	17867688
Efficient preparation of xanthine-containing oligodeoxynucleotide from oxanine-containing oligodeoxynucleotide, catalyzed by N alpha-acetyl-L-histidine.	2008	18776361
Endothelial dysfunction after long-term cold storage in HTK organ preservation solutions: effects of iron chelators and N-alpha-acetyl-L-histidine.	2008 Feb	18267229
Improvement of the cold storage of blood vessels with a vascular preservation solution. Study in porcine aortic segments.	2008 Feb	18164170
Low-density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE): detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNE.	2008 Jul	18570390
Attenuated cold storage injury of rat livers using a modified HTK solution.	2008 May 1	18314137
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines.	2008 Sep	18698849
Solution interactions between the uranyl cation [UO2(2+)] and histidine, N-acetyl-histidine, tyrosine, and N-acetyl-tyrosine.	2009 Jan	18947879
The melatonin metabolite N-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger.	2009 Jan	18643875
Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L).	2009 Jul 9	19597568
Myocardial protection with the use of L-arginine and N-alpha-acetyl-histidine.	2009 Jul-Aug	19715981
Occurrence of a novel acetylated amino acid, N(alpha)-acetylhistidine, in skeletal muscle of freshwater fish and other ectothermic vertebrates.	2009 Mar	19100335
Prostate cancer-targeted imaging using magnetofluorescent polymeric nanoparticles functionalized with bombesin.	2010 Apr	20182773
Effect of plant-based feed ingredients on osmoregulation in the Atlantic salmon lens.	2010 Apr	20044022
Deferoxamine, the newly developed iron chelator LK-614 and N-alpha-acetyl-histidine in myocardial protection.	2010 Feb	19914924
Influence of histidine on the release of all-trans retinoic acid from self-assembled glycol chitosan nanoparticles.	2010 Jul	20136494
Ability of hypochlorous acid and N-chloramines to chlorinate DNA and its constituents.	2010 Jul 19	20593802
Neuropharmacology of vestibular system disorders.	2010 Mar	20808544
N-acetylhistidine, a novel osmolyte in the lens of Atlantic salmon (Salmo salar L.).	2010 Oct	20660107
Tumor targeting efficiency of bare nanoparticles does not mean the efficacy of loaded anticancer drugs: importance of radionuclide imaging for optimization of highly selective tumor targeting polymeric nanoparticles with or without drug.	2010 Oct 15	20624433

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:04:42 GMT 2023` Edited by `admin` on `Sat Dec 16 01:04:42 GMT 2023`
Record UNII	PQ2TC3X11O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-ACETYLHISTIDINE MONOHYDRATE

Common Name

English

N-ACETYL-L-HISTIDINE HYDRATE

Brand Name

English

L-N-ACETYLHISTIDINE MONOHYDRATE

Systematic Name

English

ACETYL HISTIDINE

Official Name

English

ACETYL HISTIDINE [INCI]

Common Name

English

L-HISTIDINE, N-ACETYL-, HYDRATE (1:1)

Systematic Name

English

L-HISTIDINE, N-ACETYL-, MONOHYDRATE

Systematic Name

English

Code System Code Type Description

PUBCHEM

2724380