N-ACETYLHISTIDINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C8H11N3O3
Molecular Weight	197.1912
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)N[C@@H](CC1=CNC=N1)C(O)=O

InChI

InChIKey=KBOJOGQFRVVWBH-ZETCQYMHSA-N

InChI=1S/C8H11N3O3/c1-5(12)11-7(8(13)14)2-6-3-9-4-10-6/h3-4,7H,2H2,1H3,(H,9,10)(H,11,12)(H,13,14)/t7-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C8H11N3O3
Molecular Weight	197.1912
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Tumor targeting efficiency of bare nanoparticles does not mean the efficacy of loaded anticancer drugs: importance of radionuclide imaging for optimization of highly selective tumor targeting polymeric nanoparticles with or without drug.	2010-10-15	20624433
N-acetylhistidine, a novel osmolyte in the lens of Atlantic salmon (Salmo salar L.).	2010-10	20660107
Ability of hypochlorous acid and N-chloramines to chlorinate DNA and its constituents.	2010-07-19	20593802
Influence of histidine on the release of all-trans retinoic acid from self-assembled glycol chitosan nanoparticles.	2010-07	20136494
Prostate cancer-targeted imaging using magnetofluorescent polymeric nanoparticles functionalized with bombesin.	2010-04	20182773
Effect of plant-based feed ingredients on osmoregulation in the Atlantic salmon lens.	2010-04	20044022
Neuropharmacology of vestibular system disorders.	2010-03	20808544
Deferoxamine, the newly developed iron chelator LK-614 and N-alpha-acetyl-histidine in myocardial protection.	2010-02	19914924
Myocardial protection with the use of L-arginine and N-alpha-acetyl-histidine.	2009-09-01	19715981
Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L).	2009-07-09	19597568
Occurrence of a novel acetylated amino acid, N(alpha)-acetylhistidine, in skeletal muscle of freshwater fish and other ectothermic vertebrates.	2009-03	19100335
Solution interactions between the uranyl cation [UO2(2+)] and histidine, N-acetyl-histidine, tyrosine, and N-acetyl-tyrosine.	2009-01	18947879
The melatonin metabolite N-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger.	2009-01	18643875
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines.	2008-09	18698849
Low-density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE): detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNE.	2008-07	18570390
Attenuated cold storage injury of rat livers using a modified HTK solution.	2008-05-01	18314137
Endothelial dysfunction after long-term cold storage in HTK organ preservation solutions: effects of iron chelators and N-alpha-acetyl-L-histidine.	2008-02	18267229
Improvement of the cold storage of blood vessels with a vascular preservation solution. Study in porcine aortic segments.	2008-02	18164170
Efficient preparation of xanthine-containing oligodeoxynucleotide from oxanine-containing oligodeoxynucleotide, catalyzed by N alpha-acetyl-L-histidine.	2008	18776361
Magnetic assembly and patterning of vesicle/nanoparticle aggregates.	2007-10-10	17867688
pH-tunable equilibria in azocrown ethers with histidine moieties.	2007-09	17081808
Detection of kynurenine modifications in proteins using a monoclonal antibody.	2007-07-31	17574268
Possible bioactivation pathways of lamotrigine.	2007-07	17409271
Histidine-induced injury to cultured liver cells, effects of histidine derivatives and of iron chelators.	2007-01	17180300
N-acetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release.	2006-09-28	16935380
Purification and sequence identification of anserinase.	2005-12	16302965
Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.	2005-10	16244442
3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.	2005-06-10	15817458
Histidine nutrition and genotype affect cataract development in Atlantic salmon, Salmo salar L.	2005-06	15960659
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation.	2005-05-17	15882077
Model studies on protein side chain modification by 4-oxo-2-nonenal.	2003-04	12703968
Structural basis of protein-bound endogenous aldehydes. Chemical and immunochemical characterizations of configurational isomers of a 4-hydroxy-2-nonenal-histidine adduct.	2003-02-14	12473681
Ultraviolet spectrophotometric characterization of copper(II) complexes with imidazole N-methyl derivatives of L-histidine in aqueous solution.	2003-01-01	12509160
Mechanisms of reactions of flavin mononucleotide triplet with aromatic amino acids.	2002-07	12164501
Interaction of copper(II) with imidazole pyridine nitrogen-containing ligands in aqueous medium: a spectroscopic study.	2002-01-01	11750023
Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial cells.	2001-12	11859931
Characterization of sterically stabilized cisplatin liposomes by nuclear magnetic resonance.	2001-02-09	11342165

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:00:24 GMT 2025` Edited by `admin` on `Mon Mar 31 23:00:24 GMT 2025`
Record UNII	K9T7JPU4ML
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-ACETYLHISTIDINE

Systematic Name

English

NSC-118364

Preferred Name

English

WR-177589A

Code

English

L-HISTIDINE, N-ACETYL-

Systematic Name

English

HISTIDINE, N-ACETYL-, L-

Systematic Name

English

N-ACETYL-L-HISTIDINE

Systematic Name

English

.ALPHA.-N-ACETYL-L-HISTIDINE

Common Name

English

N.ALPHA.-ACETYL-L-HISTIDINE

Systematic Name

English

N2-ACETYLHISTIDINE

Common Name

English

N-.ALPHA.-ACETYL-L-HISTIDINE

Common Name

English

Code System Code Type Description

CHEBI

86910