Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C16H20N2OS |
| Molecular Weight | 288.408 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC3=CNC4=C3C(=CC=C4)[C@@]1([H])O[C@@H](CSC)CN2C
InChI
InChIKey=GYUHVILBXXBZDS-DJSGYFEHSA-N
InChI=1S/C16H20N2OS/c1-18-8-11(9-20-2)19-16-12-4-3-5-13-15(12)10(7-17-13)6-14(16)18/h3-5,7,11,14,16-17H,6,8-9H2,1-2H3/t11-,14-,16-/m1/s1
| Molecular Formula | C16H20N2OS |
| Molecular Weight | 288.408 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Voxergolide is a 9-oxoergoline derivative with dopamine D2 receptor agonist properties. It is induced a significant improvement in working memory performance of Roman high (RHA) avoidance strains of rats, which has high frontal cortex dopamine and DOPAC levels, hippocampal and striatal 5-HT and noradrenalin levels. Voxergolide failed to counteract the memory deficits induced by triazolam. It doesn’t counteracted scopolamine caused anterograde amnesia and sedative effects.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:58:10 GMT 2023
by
admin
on
Fri Dec 15 15:58:10 GMT 2023
|
| Record UNII |
PP012U645Q
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C221
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
6416
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY | |||
|
PP012U645Q
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY | |||
|
SUB00089MIG
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY | |||
|
3086301
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY | |||
|
100000079347
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY | |||
|
CHEMBL2104920
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY | |||
|
C66657
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY | |||
|
89651-00-3
Created by
admin on Fri Dec 15 15:58:10 GMT 2023 , Edited by admin on Fri Dec 15 15:58:10 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
