U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H10N2
Molecular Weight 122.1677
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-DIMETHYLAMINOPYRIDINE

SMILES

CN(C)C1=CC=NC=C1

InChI

InChIKey=VHYFNPMBLIVWCW-UHFFFAOYSA-N
InChI=1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

HIDE SMILES / InChI

Molecular Formula C7H10N2
Molecular Weight 122.1677
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
[Syntheses and antitumor activities of the derivatives of P-methyl goniotriol in vitro].
2002 Oct
Synthesis of an enzyme-dependent prodrug and evaluation of its potential for colon targeting.
2002 Oct
Synthesis, structural characterization and in vitro antitumor activity of novel 6-chloro-1,1-dioxo-1,4,2-benzodithiazie derivatives.
2003 Aug 15
Synthesis of starch derivatives with labile cationic groups.
2003 Jan 15
[60]fullerenoacetyl chloride as a versatile precursor for fullerene derivatives: efficient ester formation with various alcohols.
2003 Jul 24
Excited states of 4-dimethylaminopyridines: magnetic circular dichroism and computational studies.
2003 Mar
Five- to six-coordination in (nitrosyl)iron(II) porphyrinates: effects of binding the sixth ligand.
2003 Sep 8
The solution synthesis of antisense oligonucleotide-peptide conjugates directly linked via phosphoramide bond by using a fragment coupling approach.
2004
Asymmetric catalysis with "planar-chiral" derivatives of 4-(dimethylamino)pyridine.
2004 Aug
Acetylation of raw cotton for oil spill cleanup application: an FTIR and 13C MAS NMR spectroscopic investigation.
2004 Aug
Gallium halide induced heterocycle expansion of dihalodiphosphadiaryldiazanes [(XPNR)2] to the corresponding triphosphatriazanes [(XPNR)3].
2004 Dec 27
Novel polymer-supported coupling/dehydrating reagents for use in organic synthesis.
2004 Jul 21
Solid-phase synthesis of 1,2,3,4-tetrahydroisoquinoline derivatives employing support-bound tyrosine esters in the Pictet-Spengler reaction.
2004 Jul-Aug
Metalloinitiation routes to biocompatible poly(lactic acid) and poly(acrylic acid) stars with luminescent ruthenium tris(bipyridine) cores.
2004 Mar-Apr
Chemical valorization of forest and agricultural by-products. Obtention, chemical characteristics, and mechanical behavior of a novel family of hydrophobic films.
2004 May
Biologically relevant tetraazamacrocyclic complexes of manganese: synthetic, spectral, antimicrobial, antifertility and antiinflammatory approach.
2004 Nov
Steady-state and laser flash photolysis study of the carbon-carbon bond fragmentation reactions of 2-arylsulfanyl alcohol radical cations.
2004 Nov 26
Synthesis and structure of selected quaternary N-(1,4-anhydro-5-deoxy-2,3-O-isopropylidene-D,L-ribitol-5-yl)ammonium salts.
2004 Oct 4
Rational design of an L-histidine-derived minimal artificial acylase for the kinetic resolution of racemic alcohols.
2004 Oct 6
Concerning the mechanism of the ring opening of propylene oxide in the copolymerization of propylene oxide and carbon dioxide to give poly(propylene carbonate).
2004 Sep 8
Trapping 4-fluorobenzyl chloride in human plasma with chemical derivatization followed by quantitative bioanalysis using high-performance liquid chromatography/tandem mass spectrometry.
2005
Binding cooperativity of two different Lewis acid groups at the edge of ferrocene.
2005 Apr 22
Synthesis of cyclo-2,4,6-triarsa-1,3,5-triazanes from cyclo-2,4-diarsa-1,3-diazanes demonstrating the general influence of substituent steric strain on the relative stability of pnictazane oligomers.
2005 Aug 8
Luminescence ranging from red to blue: a series of copper(I)-halide complexes having rhombic {Cu2(mu-X)2} (X = Br and I) units with N-heteroaromatic ligands.
2005 Dec 26
Template-assisted cross olefin metathesis.
2005 Feb 18
Vitamin D3-based conjugates for topical treatment of psoriasis: synthesis, antiproliferative activity, and cutaneous penetration studies.
2005 Jan
Picosecond kinetics of excited-state charge separation in 4-(dimethylamino)pyridine.
2005 Jan
C5H4-BR2 bending in ferrocenylboranes: a delocalized through-space interaction between iron and boron.
2005 Jan 7
Assessment of 4-(dimethylamino)pyridine as a capping agent for gold nanoparticles.
2005 Jul 5
Preparation of biodegradable networks by photo-crosslinking lactide, epsilon-caprolactone and trimethylene carbonate-based oligomers functionalized with fumaric acid monoethyl ester.
2005 Jun
Development of cloned pig embryos by nuclear transfer following different activation treatments.
2005 Mar
Control of electron acceptor ability with ligands (L) in photoinduced electron transfer from zinc porphyrin or zinc phthalocyanine to [Ru3(mu3-O)(mu-CH3COO)6L3]+.
2005 Mar 7
Cu(II) acetate- and Mn(III) acetate-mediated radical reactions of [60]fullerene with ketonic compounds.
2005 Mar 7
Dinuclear bis-beta-diketonato ligand derivatives of iron(III) and copper(II) and use of the latter as components for the assembly of extended metallo-supramolecular structures.
2005 Mar 7
Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.
2005 Nov
Covalently networked monolayer-protected nanoparticle films.
2005 Nov 22
Synthesis and rheological properties of polylactide/poly(ethylene glycol) multiblock copolymers.
2005 Nov 4
Enantioselective total synthesis of octalactin a using asymmetric aldol reactions and a rapid lactonization to form a medium-sized ring.
2005 Nov 4
Synthesis of phosphatidylcholine: an improved method without using the cadmium chloride complex of sn-glycero-3-phosphocholine.
2005 Oct
Isopinocampheylborane derivatives with >99% ee via the DMAP complex.
2006 Aug 18
Amphiphilic poly(L-lactide)-b-dendritic poly(L-lysine)s synthesized with a metal-free catalyst and new dendron initiators: chemical preparation and characterization.
2006 Jan
Tuning the electronic communication and rates of intramolecular electron transfer of dimers of trinuclear ruthenium clusters: bridging and ancillary ligand effects.
2006 Jan 23
Esterification of 7-theophyllineacetic acid with diethylene glycol monomethyl ether.
2006 Jun
Asymmetric [3 + 2] annulations catalyzed by a planar-chiral derivative of DMAP.
2006 Jun 28
Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel.
2006 Jun 30
[Determination of T-2 toxin in cereal grains by high performance liquid chromatography with fluorescence detection after immunoaffinity column clean-up and precolumn derivatization].
2006 May
Synthesis and structural characterization of the first metal organic thallium antimonide.
2006 May 7
Surface plasmon resonance spectroscopy study of electrostatically adsorbed layers.
2006 May 9
Synthesis and characterization of hyperbranched polyglycerol hydrogels.
2006 Nov
Nucleophilicities and carbon basicities of pyridines.
2007
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:33:27 GMT 2023
Edited
by admin
on Fri Dec 15 15:33:27 GMT 2023
Record UNII
PFP1R6P0S8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4-DIMETHYLAMINOPYRIDINE
Systematic Name English
VALACYCLOVIR RELATED COMPOUND G [USP-RS]
Common Name English
VALACICLOVIR HYDROCHLORIDE IMPURITY G [EP IMPURITY]
Common Name English
VALACYCLOVIR RELATED COMPOUND G
USP   USP-RS  
Common Name English
DMAP [MI]
Common Name English
VALACYCLOVIR RELATED COMPOUND G [USP IMPURITY]
Common Name English
4-(DIMETHYLAMINO)PYRIDINE
Systematic Name English
VALACICLOVIR HYDROCHLORIDE HYDRATE IMPURITY G [EP IMPURITY]
Common Name English
N,N-DIMETHYLPYRIDIN-4-AMINE
Systematic Name English
4-DIMETHYLAMINOPYRIDINE (DMAP)
Common Name English
N,N-DIMETHYL-4-AMINOPYRIDINE
Common Name English
Code System Code Type Description
PUBCHEM
14284
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
ECHA (EC/EINECS)
214-353-5
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
WIKIPEDIA
4-DIMETHYLAMINOPYRIDINE
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
EPA CompTox
DTXSID0044369
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
MESH
C003885
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
RS_ITEM_NUM
1707894
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
CAS
1122-58-3
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
MERCK INDEX
m4703
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY Merck Index
FDA UNII
PFP1R6P0S8
Created by admin on Fri Dec 15 15:33:27 GMT 2023 , Edited by admin on Fri Dec 15 15:33:27 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (TLC)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (TLC)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
ACTIVE MOIETY