CIPROQUAZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H18N2O2
Molecular Weight	306.3584
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C=C1)N(CC3CC3)C(=O)N=C2C4=CC=CC=C4

InChI

InChIKey=VAFNJIFAZJWWNI-UHFFFAOYSA-N

InChI=1S/C19H18N2O2/c1-23-15-9-10-17-16(11-15)18(14-5-3-2-4-6-14)20-19(22)21(17)12-13-7-8-13/h2-6,9-11,13H,7-8,12H2,1H3

HIDE SMILES / InChI

Molecular Formula	C19H18N2O2
Molecular Weight	306.3584
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1267837 | https://www.ncbi.nlm.nih.gov/pubmed/309422 | https://www.ncbi.nlm.nih.gov/pubmed/291539

Ciproquazone (SL-573) is a non-steroidal anti-inflammatory drug, a derivative of quinazolinone, discovered by Sumimoto Chemical Co. in the late 1970s. Ciproquazone acts as a reversible inhibitor of prostaglandin synthetase. In animal models, ciproquazone demonstrated antipyretic, analgesic and anti-inflammatory activity. The drug was evaluated in a clinical in acute purulent diseases in the field of orodental surgery.

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:29:21 GMT 2025` Edited by `admin` on `Wed Apr 02 09:29:21 GMT 2025`
Record UNII	P8S0GE5Q4I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CIPROQUAZONE

Official Name

English

CIPROQUAZONE [JAN]

Preferred Name

English

ciproquazone [INN]

Common Name

English

1-CYCLOPROPYLMETHYL-6-METHOXY-4-PHENYL-2(1H)QUINAZOLINONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257