U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

1992
113
Substance Class Protein
Created
by admin
on Mon Mar 31 18:20:51 GMT 2025
Edited
by admin
on Mon Mar 31 18:20:51 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
P89DR4NY54
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT
Common Name English
OCTOCOG ALFA
EMA EPAR   INN   WHO-DD  
INN  
Preferred Name English
ANTIHEMOPHILIC FACTOR (RECOMBINANT), PLASMA/ALBUMIN FREE METHOD
Common Name English
RECOMBINANT ANTIHEMOPHILIC FACTOR VIII
Common Name English
KOGENATE FS
Brand Name English
KOGENATE BAYER
Brand Name English
Factor viii, recombinant [WHO-DD]
Common Name English
BAY-81-8973
Code English
ANTIHEMOPHILIC FACTOR, HUM REC
Common Name English
ADVATE
Brand Name English
ANTIHEMOPHILIC FACTOR (RECOMBINANT)
Common Name English
RECOMBINATE
Brand Name English
HUMAN FACTOR VIII RECOMBINANT
Common Name English
octocog alfa [INN]
Common Name English
BAY 14-2222
Code English
KOGENATE
Brand Name English
BAY-W-6240
Code English
BAY81-8973
Code English
ANTIHEMOPHILIC FACTOR,RECOMBINANT [VANDF]
Common Name English
RECOMBINANT ANTIHEMOPHILIC FACTOR PREPARATION
Common Name English
FACTOR VIII (RDNA)
Common Name English
ANTIHEMOPHILIC FACTOR, RECOMBINANT, MANUFACTURED PROTEIN-FREE
Common Name English
OCTOCOG ALFA [EMA EPAR]
Common Name English
KOVALTRY
Brand Name English
ANTIHEMOPHILIC FACTOR, RECOMBINANT
Common Name English
ANTIHEMOPHILIC FACTOR,RECOMBINANT
VANDF  
Common Name English
BLOOD COAGULATION FACTOR VIII HUMAN, GLYCOFORM .ALPHA.
Common Name English
BAY-14-2222
Code English
HELIXATE FS
Brand Name English
FACTOR VIII OCTOCOG ALFA [MI]
Common Name English
BAY 81-8973
Code English
HELIXATE NEXTGEN
Brand Name English
Octocog alfa [WHO-DD]
Common Name English
FACTOR VIII RECOMBIN
Common Name English
BAY W 6240
Code English
OCTOCOG ALFA [JAN]
Common Name English
Classification Tree Code System Code
EMA ASSESSMENT REPORTS HELIXATE NEXTGEN (AUTHORIZED: HEMOPHILIA A)
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
EMA ASSESSMENT REPORTS ADVATE (AUTHORIZED: HEMOPHILIA A)
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
EMA ASSESSMENT REPORTS KOGENATE BAYER (AUTHORIZED: HEMOPHILIA A)
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
NDF-RT N0000184167
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
FDA ORPHAN DRUG 280309
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
FDA ORPHAN DRUG 39289
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
FDA ORPHAN DRUG 94495
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
Code System Code Type Description
NDF-RT
N0000175979
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY Increased Coagulation Activity [PE]
RXCUI
1300486
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
INN
6959
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
CAS
139076-62-3
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
SMS_ID
100000089538
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109099
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
DAILYMED
P89DR4NY54
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
FDA UNII
P89DR4NY54
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
ChEMBL
CHEMBL2108455
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
NDF-RT
N0000007914
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY Blood Coagulation Factors [Chemical/Ingredient]
NCI_THESAURUS
C81123
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
DRUG BANK
DB00025
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
EVMPD
SUB13815MIG
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
NDF-RT
N0000006037
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY Factor VIII [Chemical/Ingredient]
MERCK INDEX
m5232
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY Merck Index
CAS
1174274-05-5
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
ALTERNATIVE
EVMPD
SUB16449MIG
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
DRUG CENTRAL
5099
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
PRIMARY
RXCUI
253151
Created by admin on Mon Mar 31 18:20:51 GMT 2025 , Edited by admin on Mon Mar 31 18:20:51 GMT 2025
ALTERNATIVE
From To
1_153 1_179
1_248 1_329
1_528 1_554
1_630 1_711
2_251 2_255
2_373 2_521
2_526 2_678
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_41
N 1_239
N 1_582
N 1_757
N 1_784
N 1_828
N 1_900
N 1_943
N 1_963
N 1_1001
N 1_1005
N 1_1055
N 1_1066
N 1_1185
N 1_1255
N 1_1259
N 1_1282
N 1_1300
N 2_62
N 2_470
Related Record Type Details
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID SUBSTITUTION [1_346] [1_718] [1_719] [1_723] [2_16] [2_32] TYROSINE Amount: TYROSINE O-SULFATE 29166358BF
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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