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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H19Cl2NO5
Molecular Weight 304.1678
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GALAMUSTINE

SMILES

O[C@H](CN(CCCl)CCCl)[C@H](O)[C@H](O)[C@@H](O)C=O

InChI

InChIKey=LXKPSLUQJMAWQY-XFWSIPNHSA-N
InChI=1S/C10H19Cl2NO5/c11-1-3-13(4-2-12)5-7(15)9(17)10(18)8(16)6-14/h6-10,15-18H,1-5H2/t7-,8+,9+,10-/m1/s1

HIDE SMILES / InChI

Molecular Formula C10H19Cl2NO5
Molecular Weight 304.1678
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Galamustine (C6-galactose mustard or C6-GLM ) is a compound that has demonstrated anti-cancer activity. Its effect on cell growth and cell cycle kinetics was studied in leukemia. Because less bone marrow toxicity was reported for this compound compared to nitrogen mustard, the development of galamustine for clinical trials in humans was considered.

Approval Year

PubMed

Substance Class Chemical
Record UNII
P771FDQ1WJ
Record Status FAILED
Record Version