TALOXIMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H16N4O2
Molecular Weight	248.281
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCOC1=NN\C(=N/O)C2=C1C=CC=C2

InChI

InChIKey=GWPPGFBGXMICEH-UHFFFAOYSA-N

InChI=1S/C12H16N4O2/c1-16(2)7-8-18-12-10-6-4-3-5-9(10)11(15-17)13-14-12/h3-6,17H,7-8H2,1-2H3,(H,13,15)

HIDE SMILES / InChI

Molecular Formula	C12H16N4O2
Molecular Weight	248.281
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4388136

Taloximine, an analeptic drug that was developed as a respiratory stimulant with bronchodilator properties. Information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
The effect of taloximine on acetylcholine bronchospasm in guinea-pigs: further evidence for a bronchodilator reflex.	1973-05	4725335
Human pharmacology of taloximine.	1970-05	5420139
Respiratory stimulants in treatment of perinatal asphyxia.	1970-02-21	4392219
Taloximine, a new respiratory stimulant with brochodilator properties.	1969-02	4388136

Sample Use Guides

In Vivo Use Guide

oral administration of 2-0 g After intravenous administration of 200 mg taloximine to one subject

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:28:21 GMT 2025` Edited by `admin` on `Mon Mar 31 18:28:21 GMT 2025`
Record UNII	P6RAI7OW7C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

taloximine [INN]

Preferred Name

English

TALOXIMINE

Official Name

English

4-(2-(DIMETHYLAMINO)ETHOXY)-1(2H)PHTHALAZINONE OXIME

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C319