TALOXIMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H16N4O2
Molecular Weight	248.281
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCOC1=NN\C(=N/O)C2=CC=CC=C12

InChI

InChIKey=GWPPGFBGXMICEH-UHFFFAOYSA-N

InChI=1S/C12H16N4O2/c1-16(2)7-8-18-12-10-6-4-3-5-9(10)11(15-17)13-14-12/h3-6,17H,7-8H2,1-2H3,(H,13,15)

HIDE SMILES / InChI

Molecular Formula	C12H16N4O2
Molecular Weight	248.281
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4388136

Taloximine, an analeptic drug that was developed as a respiratory stimulant with bronchodilator properties. Information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Taloximine, a new respiratory stimulant with brochodilator properties.	1969 Feb	4388136
Respiratory stimulants in treatment of perinatal asphyxia.	1970 Feb 21	4392219
Human pharmacology of taloximine.	1970 May	5420139
The effect of taloximine on acetylcholine bronchospasm in guinea-pigs: further evidence for a bronchodilator reflex.	1973 May	4725335

Sample Use Guides

In Vivo Use Guide

oral administration of 2-0 g After intravenous administration of 200 mg taloximine to one subject

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:27:10 GMT 2023` Edited by `admin` on `Fri Dec 15 16:27:10 GMT 2023`
Record UNII	P6RAI7OW7C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TALOXIMINE

Official Name

English

4-(2-(DIMETHYLAMINO)ETHOXY)-1(2H)PHTHALAZINONE OXIME

Systematic Name

English

taloximine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C319